product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Frizzled-8 Fc Chimera Protein, CF
catalog :
112-FZ-050
quantity :
50 ug
price :
523 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Esen E, Lee S, Wice B, Long F. PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling. J Bone Miner Res. 2015;30:1959-68 pubmed publisher
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed
Viti J, Gulacsi A, Lillien L. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2. J Neurosci. 2003;23:5919-27 pubmed
product information
brand :
R&D Systems
master code :
112-FZ
SKU :
112-FZ-050
product name :
Recombinant Mouse Frizzled-8 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse Frizzled-8 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Frizzled-8 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity, Binding Activity.
target :
Frizzled-8
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity, Binding Activity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
59-60 kDa, reducing conditions
theoretical molecular weight :
43 kDa (monomer)
gene symbol :
Fzd8
details of functionality :
Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 15-75 ng/mL in the presence of 10 ng/mL of Recombinant Mouse Wnt-3a (Catalog # 1324-WN ). Measured by its ability to bind biotinylated recombinant mouse Wnt-5a in a functional ELISA with an estimated Kd 1 nM.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q61091
applications :
Bioactivity, Binding Activity
source :
NS0-derived Recombinant Mouse Frizzled-8 Fc Chimera Protein, CF
USD :
523 USD
alt names :
frizzled (Drosophila) homolog 8, frizzled 8, frizzled family receptor 8, frizzled homolog 8 (Drosophila), frizzled-8, Frizzled8, FZ-8, FZD8, hFz8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.