product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant SARS-CoV-2 B.1.1.529 Spike His-tag Protein, CF
catalog :
11060-CV-100
quantity :
100 ug
price :
599 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Shajahan A, Pepi L, Kumar B, Murray N, Azadi P. Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern. Sci Rep. 2023;13:10053 pubmed publisher
Gallen C, Dukes C, Aldrich A, Macaisa L, Mo Q, Cubitt C, et al. Long-Term CD4+ T-Cell and Immunoglobulin G Immune Responses in Oncology Workers following COVID-19 Vaccination: An Interim Analysis of a Prospective Cohort Study. Vaccines (Basel). 2022;10: pubmed publisher
Shajahan A, Pepi L, Kumar B, Murray N, Azadi P. Site Specific N- and O-glycosylation mapping of the Spike Proteins of SARS-CoV-2 Variants of Concern. Res Sq. 2022;: pubmed publisher
product information
master code :
11060-CV
SKU :
11060-CV-100
product name :
Recombinant SARS-CoV-2 B.1.1.529 Spike His-tag Protein, CF
unit size :
100 ug
description :
The Recombinant SARS-CoV-2 B.1.1.529 Spike His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant SARS-CoV-2 B.1.1.529 Spike His-tag Protein, CF has been validated for the following applications: Bioactivity.
target :
Spike
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
SARS-CoV-2
observed molecular weight :
146-166 kDa, under reducing conditions.
theoretical molecular weight :
134 kDa
details of functionality :
Measured by its binding ability in a functional ELISA with Recombinant Human ACE-2 His-tag (Catalog # 933-ZN ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
YP_009724390.1
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived sars-cov-2 Spike protein . SARS-CoV-2 B.1.1.529 Spike . (Val16 - Lys1211) . (Ala67Val, His69del, Val70del, Thr95Ile, Gly142Asp, Val143del, Tyr144del, Tyr145del, Asn211del, Leu212Ile, ins214Glu-Pro-Glu, Gly339Asp, Ser371Leu, Ser373Pro, Ser375Phe, Lys417Asn, Asn440Lys, Gly446Ser, Ser477Asn, Thr478Lys, Glu484Ala, Gln493Arg, Gly496Ser, Gln498Arg, Asn501Tyr, Tyr505His, Thr547Lys, Asp614Gly, His655Tyr, Asn679Lys, Pro681His, Asn764Lys, Asp796Tyr, Asn856Lys, Gln954His, Asn969Lys, Leu981Phe) (Arg682Ser, Arg685Ser, Lys986Pro, Val987Pro) . Accession # YP_009724390.1 6-His tag N-terminus C-terminus
source short :
HEK293
extended description :
Omicron variant
USD :
599 USD
product details :
Omicron variant
alt names :
2019-nCoV S Protein, 2019-nCoV Spike, COVID-19 Spike, E2, Human coronavirus spike glycoprotein, Peplomer protein, S glycoprotein, S Protein, SARS-CoV-2, SARS-COV-2 S protein, SARS-COV-2 Spike glycoprotein, SARSCOV2 Spike protein, Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein, Spike glycoprotein, surface glycoprotein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.