Recombinant Human IL-20 Protein | R&D Systems 1102-IL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-20 Protein

catalog :

1102-IL

quantity :

25 ug

price :

339 USD

citations: 10

Reference
Moniruzzaman M, Wang R, Jeet V, McGuckin M, Hasnain S. Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Gough P, Ganesan S, Datta S. IL-20 Signaling in Activated Human Neutrophils Inhibits Neutrophil Migration and Function. J Immunol. 2017;198:4373-4382 pubmed publisher
Tsaousi A, Witte E, Witte K, Röwert Huber H, Volk H, Sterry W, et al. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations. Mediators Inflamm. 2016;2016:4097574 pubmed
Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, et al. Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells. Oncogene. 2017;36:1276-1286 pubmed publisher
Valentina M, Jan F, Peder N, Bo Z, Hongjie D, Pernille K. Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips. BMC Biotechnol. 2015;15:73 pubmed publisher
Heinemann A, He Y, Zimina E, Boerries M, Busch H, Chmel N, et al. Induction of phenotype modifying cytokines by FERMT1 mutations. Hum Mutat. 2011;32:397-406 pubmed publisher
Wolk K, Witte E, Warszawska K, Schulze Tanzil G, Witte K, Philipp S, et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol. 2009;39:3570-81 pubmed publisher
Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol. 2009;39:2779-88 pubmed publisher
Wolk K, Witte K, Witte E, Proesch S, Schulze Tanzil G, Nasilowska K, et al. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J Leukoc Biol. 2008;83:1181-93 pubmed publisher
Sa S, Valdez P, Wu J, Jung K, Zhong F, Hall L, et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007;178:2229-40 pubmed

product information

brand :

R&D Systems

master code :

1102-IL

SKU :

1102-IL-025

product name :

Recombinant Human IL-20 Protein

description :

The Recombinant Human IL-20 Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-20 Protein has been validated for the following applications: Bioactivity.

target :

IL-20

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

17.6 kDa

gene symbol :

IL20

details of functionality :

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta . The ED50 for this effect is 0.05-0.3 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

1102-IL

accessionNumbers :

AAF36679

applications :

Bioactivity

source :

E. coli -derived human IL-20 protein Leu25-Glu176, with an N-terminal Met

2020 USD :

339

2021 USD :

339 USD

alt names :

Cytokine Zcyto10, IL10D, IL20, IL-20ZCYTO10four alpha helix cytokine, interleukin 20, interleukin-20, MGC96907

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.