Recombinant Human Endostatin Protein, CF | R&D Systems 1098-ES-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Endostatin Protein, CF

catalog :

1098-ES-050

quantity :

50 ug

price :

400 USD

citations: 2

Reference
Herrera Millar V, Canciani B, Mangiavini L, Filipe J, Aidos L, Pallaoro M, et al. Endostatin in 3D Fibrin Hydrogel Scaffolds Promotes Chondrogenic Differentiation in Swine Neonatal Meniscal Cells. Biomedicines. 2022;10: pubmed publisher
Nagy N, Barad C, Hotta R, Bhave S, Arciero E, DORA D, et al. Collagen 18 and agrin are secreted by neural crest cells to remodel their microenvironment and regulate their migration during enteric nervous system development. Development. 2018;145: pubmed publisher

product information

master code :

1098-ES

SKU :

1098-ES-050

product name :

Recombinant Human Endostatin Protein, CF

unit size :

50 ug

description :

The Recombinant Human Endostatin Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Endostatin Protein, CF has been validated for the following applications: Bioactivity.

target :

Endostatin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

21 kDa, reducing conditions

theoretical molecular weight :

21.6 kDa

gene symbol :

COL18A1

details of functionality :

Measured by its ability to inhibit the FGF basic-dependent proliferation of HUVEC human umbilical vein endothelial cells. Dhanabal, M. et al . (1999) Biochem. Biophys. Res. Commun. 258 :345. The ED50 for this effect is 0.4-2 ╡g/mL in the presence of 20 ╡g/mL of Goat Anti-Human Endostatin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1098 ).

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_569712

applications :

Bioactivity

source long :

E. coli -derived human Endostatin protein His1154-Ser1335, with an N-terminal Met and 8-His tag

source short :

E. coli

USD :

400 USD

alt names :

antiangiogenic agent, COL18A1, collagen alpha-1(XVIII) chain, collagen, type XVIII, alpha 1, FLJ27325, FLJ34914, human type XVIII collagen10endostatin, KNO, KNO1MGC74745, Knobloch syndrome, type 1, KS, multi-functional protein MFP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.