This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein
catalog :
1089-R2
quantity :
25 ug
price :
339 USD
citations: 2
Reference
Steeland S, Puimège L, Vandenbroucke R, Van Hauwermeiren F, Haustraete J, Devoogdt N, et al. Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1. J Biol Chem. 2015;290:4022-37 pubmed publisher
Copeland S, Siddiqui J, Remick D. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J Immunol Methods. 2004;284:99-106 pubmed
product information
brand :
R&D Systems
master code :
1089-R2
SKU :
1089-R2-025
product name :
Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein
description :
The Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein from R&D Systems is derived from E. coli. The Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein has been validated for the following applications: Bioactivity.
target :
TNF RII/TNFRSF1B
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
20 kDa
gene symbol :
TNFRSF1B
details of functionality :
Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 0.2-0.6 µg/mL in the presence of 0.25 ng/mL rhTNF-alpha .
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
1089-R2
accessionNumbers :
AAA36755
applications :
Bioactivity
source :
E. coli -derived human TNF RII/TNFRSF1B protein Pro24-Thr206
2020 USD :
339
2021 USD :
339 USD
alt names :
CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.