Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein | R&D Systems 1089-R2-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein

catalog :

1089-R2-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Baram T, Oren N, Erlichman N, Meshel T, Ben Baruch A. Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer. Cancers (Basel). 2022;14: pubmed publisher
Clausen B, Wirenfeldt M, Høgedal S, Frich L, Nielsen H, Schrøder H, et al. Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke. Acta Neuropathol Commun. 2020;8:81 pubmed publisher
Steeland S, PuimÃ¨ge L, Vandenbroucke R, Van Hauwermeiren F, Haustraete J, Devoogdt N, et al. Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1. J Biol Chem. 2015;290:4022-37 pubmed publisher
Copeland S, Siddiqui J, Remick D. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J Immunol Methods. 2004;284:99-106 pubmed

product information

brand :

R&D Systems

master code :

1089-R2

SKU :

1089-R2-025

product name :

Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein

unit size :

25 ug

seo description :

The Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein from R&D Systems is derived from E. coli. The Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein has been validated for the following applications: Bioactivity.

target :

TNF RII/TNFRSF1B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

20 kDa

gene symbol :

TNFRSF1B

details of functionality :

Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews,áN. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 0.2-0.6 ╡g/mL in the presence of 0.25 ng/mL rhTNF-alpha .

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAA36755

applications :

Bioactivity

source :

E. coli-derived Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein

USD :

432 USD

alt names :

CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage