Recombinant Human BMP-8a Protein, CF | R&D Systems 1073-BP-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human BMP-8a Protein, CF

catalog :

1073-BP-010/CF

quantity :

10 ug

price :

436 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Wang X, Xiang Y, Yu Y, Wang R, Zhang Y, Xu Q, et al. Formative pluripotent stem cells show features of epiblast cells poised for gastrulation. Cell Res. 2021;31:526-541 pubmed publisher
Senft A, Bikoff E, Robertson E, Costello I. Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse. Nat Commun. 2019;10:1089 pubmed publisher
Senft A, Costello I, King H, Mould A, Bikoff E, Robertson E. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming. Cell Rep. 2018;24:1977-1985.e7 pubmed publisher
Jung D, Xiong J, Ye M, Qin X, Li L, Cheng S, et al. In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells. Nat Commun. 2017;8:15680 pubmed publisher
Dominguez A, Chiang H, Sukhwani M, Orwig K, Reijo Pera R. Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies. Sci Rep. 2014;4:6432 pubmed publisher
Sharma A, Huard C, Vernochet C, Ziemek D, Knowlton K, Tyminski E, et al. Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6. PLoS ONE. 2014;9:e92608 pubmed publisher
Goyal A, CHAVEZ S, Reijo Pera R. Generation of human induced pluripotent stem cells using epigenetic regulators reveals a germ cell-like identity in partially reprogrammed colonies. PLoS ONE. 2013;8:e82838 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Geens M, Sermon K, Van De Velde H, Tournaye H. Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells. J Assist Reprod Genet. 2011;28:471-80 pubmed publisher

product information

brand :

R&D Systems

master code :

1073-BP/CF

SKU :

1073-BP-010/CF

product name :

Recombinant Human BMP-8a Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human BMP-8a Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human BMP-8a Protein, CF has been validated for the following applications: Binding Activity.

target :

BMP-8a

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

15.8 kDa (monomer)

gene symbol :

BMP8B

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human BMP-8a is present at 1 ╡g/mL, the concentration of recombinant human BMPR-1A Fc Chimera that produces 50% of the optimal binding response is approximately 1.5-6 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAP74559

applications :

Binding Activity

source :

E. coli-derived Recombinant Human BMP-8a Protein, CF

USD :

436 USD

alt names :

BMP-8A, bone morphogenetic protein 8a, Op2, Osteogenic Protein 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage