Recombinant Mouse FGL2 HA-tag Protein, CF | R&D Systems 10691-FL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse FGL2 HA-tag Protein, CF

catalog :

10691-FL-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Zhao Y, Xiang Z, Pan H, Huang X, Chen W, Huang Z. FGL2 improves experimental colitis related to gut microbiota structure and bile acid metabolism by regulating macrophage autophagy and apoptosis. Heliyon. 2024;10:e34349 pubmed publisher
Bennion K, Liu D, Dawood A, Wyatt M, Alexander K, Abdel Hakeem M, et al. CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB. Nat Commun. 2024;15:5280 pubmed publisher
Rasquinha M, Lasrado N, Petro Turnquist E, Weaver E, Venkataraman T, Anderson D, et al. PhIP-Seq Reveals Autoantibodies for Ubiquitously Expressed Antigens in Viral Myocarditis. Biology (Basel). 2022;11: pubmed publisher

product information

master code :

10691-FL

SKU :

10691-FL-050

product name :

Recombinant Mouse FGL2 HA-tag Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse FGL2 HA-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse FGL2 HA-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

FGL2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

61-72 kDa, under reducing conditions

theoretical molecular weight :

48 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse Fc gamma RIIB/CD32b (Catalog # 1460-CD ) is immobilized at 1 ╡g/mL (100 ╡L/well), Recombinant Mouse FGL2 HA-tag (Catalog # 10691-FL) binds with an ED50 of 0.1-0.8 ╡g/mL. Measured by its ability to inhibit anti-CD3-induced proliferation of mouse T lymphocytes. The ED50 for this effect is 1.5-12 ╡g/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P12804.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse FGL2 protein Hemagglutinin Tag (YPYDVPDYA) Mouse FGL2 (Val20-Pro432) Accession # P12804.1 N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

fibrinogen-like 2, Fibrinogen-like protein 2, fibroleukin, pT49T49, T49

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage