This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Epiregulin Protein
catalog :
1068-EP-050
quantity :
50 ug
price :
432 USD
citations: 9
Reference
Pellon Cardenas O, Rout P, Hassan S, Fokas E, Ping H, Patel I, et al. Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium. bioRxiv. 2025;: pubmed publisher
Gong X, Shen L, Zhang H, Ai J, Gilchrist R, Zhao Y. CAPA-IVM improves the cytoplasmic quality of in vitro-matured oocytes from unstimulated mice. Theriogenology. 2023;212:117-128 pubmed publisher
Dom xe8 nech Moreno E, Brandt A, Lemmetyinen T, Wartiovaara L, M xe4 kel xe4 T, Ollila S. Tellu - an object-detector algorithm for automatic classification of intestinal organoids. Dis Model Mech. 2023;16: pubmed publisher
Wang Y, Leng X, Zhou C, Lu S, Tsang C, Xu J, et al. Non-enzymatic role of SOD1 in intestinal stem cell growth. Cell Death Dis. 2022;13:882 pubmed publisher
Westendorp F, Karpus O, Koelink P, Vermeulen J, Meisner S, Koster J, et al. Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation. Oncogene. 2021;40:1628-1643 pubmed publisher
Martin L, Smith S, Khoutorsky A, Magnussen C, Samoshkin A, Sorge R, et al. Epiregulin and EGFR interactions are involved in pain processing. J Clin Invest. 2017;127:3353-3366 pubmed publisher
Shuhaibar L, Egbert J, Edmund A, Uliasz T, Dickey D, Yee S, et al. Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone. Dev Biol. 2016;409:194-201 pubmed publisher
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed publisher
Patel R, Kim D, Peters J, Perdew G. The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin. Toxicol Sci. 2006;89:75-82 pubmed
product information
master code :
1068-EP
SKU :
1068-EP-050
product name :
Recombinant Mouse Epiregulin Protein
unit size :
50 ug
description :
The Recombinant Mouse Epiregulin Protein from R&D Systems is derived from E. coli. The Recombinant Mouse Epiregulin Protein has been validated for the following applications: Bioactivity.
target :
Epiregulin
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
theoretical molecular weight :
5.5 kDa
gene symbol :
Ereg
details of functionality :
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al . (1991) Proc. Natl. Acad. Sci. USA 88 :415. The ED50 for this effect is 0.3-1 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_031976
applications :
Bioactivity
source long :
E. coli -derived mouse Epiregulin protein Val56-Leu101, with an N-terminal Met
source short :
E. coli
USD :
432 USD
alt names :
epiregulin, ER, EREG, proepiregulin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.