Recombinant Human Adiponectin/Acrp30 Protein, CF | R&D Systems 1065-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Adiponectin/Acrp30 Protein, CF

catalog :

1065-AP

quantity :

50 ug

price :

329 USD

citations: 18

Reference
Miranda Martinez A, Mercado Gómez O, Arriaga Ávila V, Guevara Guzmán R. Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression. Int J Endocrinol. 2017;2017:4892609 pubmed publisher
Rak A, Zajda K, Gregoraszczuk E. Endocrine disrupting compounds modulates adiponectin secretion, expression of its receptors and action on steroidogenesis in ovarian follicle. Reprod Toxicol. 2017;69:204-211 pubmed publisher
Gasbarrino K, Zheng H, Hafiane A, Veinot J, Lai C, Daskalopoulou S. Decreased Adiponectin-Mediated Signaling Through the AdipoR2 Pathway Is Associated With Carotid Plaque Instability. Stroke. 2017;48:915-924 pubmed publisher
Fu S, Xu H, Gu M, Liu C, Wang Q, Wan X, et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep. 2017;7:43771 pubmed publisher
Ito R, Narita S, Huang M, Nara T, Numakura K, Takayama K, et al. The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the "obesity paradox". PLoS ONE. 2017;12:e0171615 pubmed publisher
Nokhbehsaim M, Keser S, Nogueira A, Cirelli J, Jepsen S, Jager A, et al. Beneficial effects of adiponectin on periodontal ligament cells under normal and regenerative conditions. J Diabetes Res. 2014;2014:796565 pubmed publisher
Chen H, Tsou H, Chen J, Shih J, Chen Y, Tang C. Adiponectin enhances intercellular adhesion molecule-1 expression and promotes monocyte adhesion in human synovial fibroblasts. PLoS ONE. 2014;9:e92741 pubmed publisher
Lavoie V, Kernaleguen A, Charron G, Farhat N, Cossette M, Mamarbachi A, et al. Functional effects of adiponectin on endothelial progenitor cells. Obesity (Silver Spring). 2011;19:722-8 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
von Eynatten M, Liu D, Hock C, Oikonomou D, Baumann M, Allolio B, et al. Urinary adiponectin excretion: a novel marker for vascular damage in type 2 diabetes. Diabetes. 2009;58:2093-9 pubmed publisher
Weigert J, Neumeier M, Wanninger J, Schober F, Sporrer D, Weber M, et al. Adiponectin upregulates monocytic activin A but systemic levels are not altered in obesity or type 2 diabetes. Cytokine. 2009;45:86-91 pubmed publisher
Araki H, Nishihara T, Matsuda M, Fukuhara A, Kihara S, Funahashi T, et al. Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet. Gut. 2008;57:1431-40 pubmed publisher
Qiao L, Zou C, van der Westhuyzen D, Shao J. Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism. Diabetes. 2008;57:1824-33 pubmed publisher
Klamer A, Skogstrand K, Hougaard D, Nørgaard Petersen B, Juul A, Greisen G. Adiponectin levels measured in dried blood spot samples from neonates born small and appropriate for gestational age. Eur J Endocrinol. 2007;157:189-94 pubmed
Han R, Lai R, Ding Q, Wang Z, Luo X, Zhang Y, et al. Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism. Diabetologia. 2007;50:1960-1968 pubmed publisher
Ehling A, Schaffler A, Herfarth H, Tarner I, Anders S, Distler O, et al. The potential of adiponectin in driving arthritis. J Immunol. 2006;176:4468-78 pubmed
Rovin B, Song H. Chemokine induction by the adipocyte-derived cytokine adiponectin. Clin Immunol. 2006;120:99-105 pubmed
Iversen P, Wiig H. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. Clin Cancer Res. 2005;11:6793-9 pubmed

product information

brand :

R&D Systems

master code :

1065-AP

SKU :

1065-AP-050

product name :

Recombinant Human Adiponectin/Acrp30 Protein, CF

description :

The Recombinant Human Adiponectin/Acrp30 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Adiponectin/Acrp30 Protein, CF has been validated for the following applications: Bioactivity.

target :

Adiponectin/Acrp30

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Supplied as a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

36 kDa, reducing conditions

theoretical molecular weight :

25.4 kDa

gene symbol :

ADIPOQ

details of functionality :

Measured by its ability to inhibit glucose production by rat hepatocytes. Zhou, H. et al . (2005) Biochem. Biophys. Res. Commun. 338 :793. The ED50 for this effect is 4-20 µg/mL. Measured by its ability to induce TIMP-1 secretion by mouse macrophages. Kumada, M. et al . (2004) Circulation 109 :2046. The ED50 for this effect is 1-5 µg/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

1065-AP

accessionNumbers :

Q15848

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human Adiponectin/Acrp30 protein Glu19-Asn244, with a C-terminal 6-His tag

2020 USD :

329

2021 USD :

329 USD

alt names :

ACDC, Acrp30, ACRP30ADPN, adipocyte, C1Q and collagen domain containing, adiponectin, adiponectin, C1Q and collagen domain containing, AdipoQ, ADIPQTL1, apM-1, ApM1, APM1APM-1, C1q and collagen domain-containing protein, GBP28, GBP28apM1, Gelatin-binding protein

storage :

Do not freeze. 6 months from date of receipt, 2 to 8 °C as supplied.