product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse PDGF R alpha Fc Chimera Protein, CF
catalog :
1062-PR-050
quantity :
50 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Hong X, Jian Y, Ding S, Zhou J, Zheng X, Zhang H, et al. Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke. EBioMedicine. 2023;87:104406 pubmed publisher
Yang X, Chrisman H, Weijer C. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008;135:3521-30 pubmed publisher
product information
master code :
1062-PR
SKU :
1062-PR-050
product name :
Recombinant Mouse PDGF R alpha Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse PDGF R alpha Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse PDGF R alpha Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
PDGF R alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
125-140 kDa, reducing conditions
theoretical molecular weight :
82.5 kDa (monomer)
gene symbol :
Pdgfra
details of functionality :
Measured by its ability to inhibit the biological activity of PDGF-AB or PDGF-AA using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.01-0.04 ╡g/mL in the presence of 10 ng/mL recombinant human PDGF-AA.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P26618.3
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse PDGF R alpha protein Mouse PDGF R alpha Leu25-Glu524 (Asp65Glu, Gly439Ala, Thr440Ala) Accession # P26618.3 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
468 USD
alt names :
alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, EC 2.7.10, EC 2.7.10.1, MGC74795, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PDGF-R-alpha, platelet-derived growth factor receptor, alpha polypeptide, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein, RHEPDGFRA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.