product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Decorin Protein, CF
catalog :
1060-DE-100
quantity :
100 ug
price :
408 USD
more info or order :
R&D Systems product webpage
citations: 12
Reference
Chatterjee J, Koleske J, Chao A, Sauerbeck A, Chen J, Qi X, et al. Brain injury drives optic glioma formation through neuron-glia signaling. Acta Neuropathol Commun. 2024;12:21 pubmed publisher
Wang J, Ocadiz Ruiz R, Hall M, Bushnell G, Orbach S, Decker J, et al. A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs. Nat Commun. 2023;14:4790 pubmed publisher
Jiang R, Smailovic U, Haytural H, Tijms B, Li H, Haret R, et al. Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's Aβ amyloidosis. Acta Neuropathol Commun. 2022;10:96 pubmed publisher
Liu J, Zhu S, Zeng L, Li J, Klionsky D, Kroemer G, et al. DCN released from ferroptotic cells ignites AGER-dependent immune responses. Autophagy. 2021;:1-14 pubmed publisher
Chatterjee J, Sanapala S, Cobb O, Bewley A, Goldstein A, Cordell E, et al. Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia. Nat Commun. 2021;12:7122 pubmed publisher
Daquinag A, Gao Z, Fussell C, Sun K, Kolonin M. Glycosaminoglycan Modification of Decorin Depends on MMP14 Activity and Regulates Collagen Assembly. Cells. 2020;9: pubmed publisher
Cartee N, Wang M. Binding of omeprazole to protein targets identified by monoclonal antibodies. PLoS ONE. 2020;15:e0239464 pubmed publisher
Zhao M, Mantel I, Gélizé E, Li X, XIE X, Arboleda A, et al. Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration. Nat Commun. 2019;10:369 pubmed publisher
Daquinag A, Dadbin A, Snyder B, Wang X, Sahin A, Ueno N, et al. Non-glycanated Decorin Is a Drug Target on Human Adipose Stromal Cells. Mol Ther Oncolytics. 2017;6:1-9 pubmed publisher
Sneddon J, Borowiak M, Melton D. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 2012;491:765-8 pubmed publisher
Ichii M, Frank M, Iozzo R, Kincade P. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood. 2012;119:1683-92 pubmed publisher
Daquinag A, Zhang Y, Amaya Manzanares F, Simmons P, Kolonin M. An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells. Cell Stem Cell. 2011;9:74-86 pubmed publisher
product information
brand :
R&D Systems
master code :
1060-DE
SKU :
1060-DE-100
product name :
Recombinant Mouse Decorin Protein, CF
unit size :
100 ug
seo description :
The Recombinant Mouse Decorin Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Decorin Protein, CF has been validated for the following applications: Bioactivity.
target :
Decorin
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
40-45 kDa, reducing conditions
theoretical molecular weight :
39 kDa
gene symbol :
Dcn
details of functionality :
Measured by its ability to modulate collagen fibrillogenesis. Ge, G. et al . (2004) J. Biol. Chem. 279 :41626. 5 ╡g/mL of Recombinant Mouse Decorin can significantly delay the rate of collagen fibrillogenesis.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P28654
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Decorin Protein, CF
USD :
408 USD
alt names :
Bone proteoglycan II, CSCD, DCN, decorin, decorin proteoglycan, dermatan sulphate proteoglycans II, DSPG2, PG40, PGII, PG-II, PGS2, PG-S2, proteoglycan core protein, SLRR1B, SLRR1BPGS2, small leucine-rich protein 1B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.