Recombinant Rat Notch-1 Fc Chimera Protein, CF | R&D Systems 1057-TK-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Notch-1 Fc Chimera Protein, CF

catalog :

1057-TK-050

quantity :

50 ug

price :

468 USD

citations: 4

Reference
Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
Greene M, Lai Y, Pajcini K, Bailis W, Pear W, Lancaster E. Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand. PLoS ONE. 2016;11:e0161157 pubmed publisher
Sneddon J, Borowiak M, Melton D. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 2012;491:765-8 pubmed publisher
Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells. J Immunol. 2006;177:5041-50 pubmed

product information

master code :

1057-TK

SKU :

1057-TK-050

product name :

Recombinant Rat Notch-1 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Rat Notch-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Notch-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Notch-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

observed molecular weight :

117 kDa, reducing conditions

theoretical molecular weight :

76 kDa (monomer)

gene symbol :

Notch1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rrNotch-1/Fc Chimera can bind rrJagged-1/Fc Chimera with an apparent KD 5 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q07008.2

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived rat Notch-1 protein Rat Notch-1 Arg20 - Glu488 (Ala208Thr Asp334Glu) Accession #Q07008.2 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

468 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.