product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat Notch-1 Fc Chimera Protein, CF
catalog :
1057-TK-050
quantity :
50 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
Greene M, Lai Y, Pajcini K, Bailis W, Pear W, Lancaster E. Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand. PLoS ONE. 2016;11:e0161157 pubmed publisher
Sneddon J, Borowiak M, Melton D. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 2012;491:765-8 pubmed publisher
Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells. J Immunol. 2006;177:5041-50 pubmed
product information
brand :
R&D Systems
master code :
1057-TK
SKU :
1057-TK-050
product name :
Recombinant Rat Notch-1 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Rat Notch-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Notch-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Notch-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
observed molecular weight :
117 kDa, reducing conditions
theoretical molecular weight :
76 kDa (monomer)
gene symbol :
Notch1
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized rrNotch-1/Fc Chimera can bind rrJagged-1/Fc Chimera with an apparent KD 5 nM.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q07008.2
applications :
Binding Activity
source :
NS0-derived Recombinant Rat Notch-1 Fc Chimera Protein, CF
USD :
468 USD
alt names :
EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.