product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat TrkA Fc Chimera Protein, CF
catalog :
1056-TK-050
quantity :
50 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Domingues H, Urbanski M, Macedo Ribeiro S, Almaktari A, Irfan A, Hernandez Y, et al. Pushing myelination: developmental regulation of myosin expression drives oligodendrocyte morphological differentiation. J Cell Sci. 2020;: pubmed publisher
Kalous A, Nangle M, Anastasía A, Hempstead B, Keast J. Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF. J Neurochem. 2012;122:523-36 pubmed publisher
Kim Y, Chen J, Langen R, Chan J. Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis. Nat Protoc. 2010;5:1396-405 pubmed publisher
product information
brand :
R&D Systems
master code :
1056-TK
SKU :
1056-TK-050
product name :
Recombinant Rat TrkA Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Rat TrkA Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat TrkA Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TrkA
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
observed molecular weight :
120-130 kDa, reducing conditions
theoretical molecular weight :
69 kDa (monomer)
gene symbol :
Ntrk1
details of functionality :
Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 10-40 ng/mL in the presence of 10 ng/mL of rrNGF.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P35739
applications :
Bioactivity
source :
NS0-derived Recombinant Rat TrkA Fc Chimera Protein, CF
USD :
456 USD
alt names :
DKFZp781I14186, EC 2.7.10, EC 2.7.10.1, MTChigh affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, NTRK1, NTRK-1, p140-TrkA, TRK1-transforming tyrosine kinase protein, Trk-A, TRKAOncogene TRK, TRKTRK1, tyrosine kinase receptor A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.