Recombinant Rat TrkA Fc Chimera Protein, CF | R&D Systems 1056-TK-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat TrkA Fc Chimera Protein, CF

catalog :

1056-TK-050

quantity :

50 ug

price :

456 USD

citations: 3

Reference
Domingues H, Urbanski M, Macedo Ribeiro S, Almaktari A, Irfan A, Hernandez Y, et al. Pushing myelination: developmental regulation of myosin expression drives oligodendrocyte morphological differentiation. J Cell Sci. 2020;: pubmed publisher
Kalous A, Nangle M, Anastasía A, Hempstead B, Keast J. Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF. J Neurochem. 2012;122:523-36 pubmed publisher
Kim Y, Chen J, Langen R, Chan J. Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis. Nat Protoc. 2010;5:1396-405 pubmed publisher

product information

master code :

1056-TK

SKU :

1056-TK-050

product name :

Recombinant Rat TrkA Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Rat TrkA Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat TrkA Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TrkA

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

observed molecular weight :

120-130 kDa, reducing conditions

theoretical molecular weight :

69 kDa (monomer)

gene symbol :

Ntrk1

details of functionality :

Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 10-40 ng/mL in the presence of 10 ng/mL of rrNGF.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P35739

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived rat TrkA protein Rat TrkA (Ala33 - Pro418) (Ala34 - Pro418) Accession # P35739 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

DKFZp781I14186, EC 2.7.10, EC 2.7.10.1, MTChigh affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, NTRK1, NTRK-1, p140-TrkA, TRK1-transforming tyrosine kinase protein, Trk-A, TRKAOncogene TRK, TRKTRK1, tyrosine kinase receptor A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.