product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat PDGF-AA Protein, CF
catalog :
1055-AA-050
quantity :
50 ug
price :
348 USD
more info or order :
R&D Systems product webpage
citations: 12
Reference
Yao L, Rathnakar B, Kwon H, Sakashita H, Kim J, Rackley A, et al. Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing. Cell Rep. 2022;40:111192 pubmed publisher
Shimizu T, Murakoshi H, Matsumoto H, Ichino K, Hattori A, Ueno S, et al. Tension Sensor Based on Fluorescence Resonance Energy Transfer Reveals Fiber Diameter-Dependent Mechanical Factors During Myelination. Front Cell Neurosci. 2021;15:685044 pubmed publisher
Kadrmas J, Beckerle M, Yoshigi M. Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha. Sci Rep. 2020;10:19303 pubmed publisher
Hao X, Guan X, Zhao X, Ji M, Wen X, Chen P, et al. Phthalate inhibits Leydig cell differentiation and promotes adipocyte differentiation. Chemosphere. 2021;262:127855 pubmed publisher
Ogawa S, Hagiwara M, Misumi S, Tajiri N, Shimizu T, Ishida A, et al. Transplanted Oligodendrocyte Progenitor Cells Survive in the Brain of a Rat Neonatal White Matter Injury Model but Less Mature in Comparison with the Normal Brain. Cell Transplant. 2020;29:963689720946092 pubmed publisher
Guan X, Chen P, Zhao X, Hao X, Chen F, Ji M, et al. Characterization of stem cells associated with seminiferous tubule of adult rat testis for their potential to form Leydig cells. Stem Cell Res. 2019;41:101593 pubmed publisher
López Bellido R, Puig S, Huang P, Tsai C, Turner H, Galko M, et al. Growth factor signaling regulates mechanical nociception in flies and vertebrates. J Neurosci. 2019;: pubmed publisher
Tao C, Zhang X. Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016;17:1832-1844 pubmed publisher
Poehler A, Xiang W, Spitzer P, May V, Meixner H, Rockenstein E, et al. Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment. Autophagy. 2014;10:2171-92 pubmed publisher
Yang J, Wang J, Pan L, Li H, Rao C, Zhang X, et al. BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells. Exp Cell Res. 2014;320:54-61 pubmed publisher
Schneider L, Stock C, Dieterich P, Jensen B, Pedersen L, Satir P, et al. The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium. J Cell Biol. 2009;185:163-76 pubmed publisher
Yang X, Chrisman H, Weijer C. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008;135:3521-30 pubmed publisher
product information
brand :
R&D Systems
master code :
1055-AA
SKU :
1055-AA-050
product name :
Recombinant Rat PDGF-AA Protein, CF
unit size :
50 ug
seo description :
The Recombinant Rat PDGF-AA Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat PDGF-AA Protein, CF has been validated for the following applications: Bioactivity.
target :
PDGF-AA
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
theoretical molecular weight :
12.5 kDa (monomer)
gene symbol :
Pdgfa
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 3-9 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
AAB59693.1
applications :
Bioactivity
source :
E. coli-derived Recombinant Rat PDGF-AA Protein, CF
USD :
348 USD
alt names :
PDGF1, PDGF-A, PDGFAA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.