product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ACE-2 Fc Chimera Protein, CF
catalog :
10544-ZN-020
quantity :
20 ug (also 100 ug)
price :
432 USD
more info or order :
citations: 2
Reference
Loi L, Yang C, Lin Y, Su Y, Juan Y, Chen Y, et al. Decoy peptides effectively inhibit the binding of SARS-CoV-2 to ACE2 on oral epithelial cells. Heliyon. 2023;9:e22614 pubmed publisher
Hoffmann M, Wong L, Arora P, Zhang L, Rocha C, Odle A, et al. Omicron subvariant BA.5 efficiently infects lung cells. Nat Commun. 2023;14:3500 pubmed publisher
product information
brand :
R&D Systems
master code :
10544-ZN
SKU :
10544-ZN-020
product name :
Recombinant Human ACE-2 Fc Chimera Protein, CF
unit size :
20 ug (also 100 ug)
seo description :
The Recombinant Human ACE-2 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human ACE-2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity, Enzyme Activity.
target :
ACE-2
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris, NaCl, ZnCl2 and Glycerol.
conjugate :
Unconjugated
dilution :
Bioactivity, Enzyme Activity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
124-130 kDa, under reducing conditions
theoretical molecular weight :
110 kDa
details of functionality :
Measured by its binding ability in a functional ELISA with Recombinant Viral SARS-CoV-2 S Protein RBD Fc Chimera (Catalog # 10499-CV ). Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007 ). The specific activity is 550 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human ACE-2 Fc Chimera Protein Binding Activity
accessionNumbers :
Q9BYF1.2
applications :
Bioactivity, Enzyme Activity
source :
CHO-derived Recombinant Human ACE-2 Fc Chimera Protein, CF
extended description :
Bioactive, High Spike RBD Binding
USD :
432 USD
product details :
Bioactive, High Spike RBD Binding
alt names :
ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.