product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Cynomolgus Monkey ErbB2/Her2 Fc Protein, CF
catalog :
10526-ER-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
product information
master code :
10526-ER
SKU :
10526-ER-050
product name :
Recombinant Cynomolgus Monkey ErbB2/Her2 Fc Protein, CF
unit size :
50 ug
description :
The Recombinant Cynomolgus Monkey ErbB2/Her2 Fc Protein, CF from R&D Systems is derived from CHO. The Recombinant Cynomolgus Monkey ErbB2/Her2 Fc Protein, CF has been validated for the following applications: Bioactivity.
target :
ErbB2/Her2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Cynomolgus Monkey
observed molecular weight :
115-140 kDa, under reducing conditions
theoretical molecular weight :
96 kDa
details of functionality :
Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer cell proliferation. Brodowicz, T. et al . (1997) Int. J. Cancer 73 :875. The ED50 for this effect is 0.2-1.2 ╡g/mL in the presence of 0.6 ╡g/mL Anti-Human ErbB2/Her2 Monoclonal Antibody (Trastuzumab, Catalog # MAB9589 ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Cynomolgus Monkey ErbB2/Her2 Fc Protein SDS-PAGE
accessionNumbers :
XP_005584091.2
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey ErbB2/Her2 protein Cynomolgus Monkey ErbB2/Her2 (Thr23-Thr652) Accession # XP_005584091.2 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
CHO
USD :
432 USD
alt names :
CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, Neu Oncogene, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGL, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.