Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF | R&D Systems 1049-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF

catalog :

1049-SE-010

quantity :

10 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Chazot A, Zimberger C, Feracci M, Moussa A, Good S, Sommadossi J, et al. The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution. PLoS Biol. 2024;22:e3002743 pubmed publisher
Li J, Liu S, Shi J, Zhu H. Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection. Pharmaceutics. 2021;13: pubmed publisher
Luu A, Wong C, Agrawal V, Wise N, Handyside B, Lo M, et al. Intermittent enzyme replacement therapy with recombinant human β-galactosidase prevents neuraminidase 1 deficiency. J Biol Chem. 2020;295:13556-13569 pubmed publisher
Murakami E, Tolstykh T, Bao H, Niu C, Steuer H, Bao D, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem. 2010;285:34337-47 pubmed publisher
Reich M, Spindler K, Burret M, Kalbacher H, Boehm B, Burster T. Cathepsin A is expressed in primary human antigen-presenting cells. Immunol Lett. 2010;128:143-7 pubmed publisher

product information

brand :

R&D Systems

master code :

1049-SE

SKU :

1049-SE-010

product name :

Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF

unit size :

10 ug

seo description :

The Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF from R&D Systems is derived from NS0. The Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF has been validated for the following applications: Enzyme Activity.

target :

Cathepsin A/Lysosomal Carboxypeptidase A

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

51-62 kDa, reducing conditions

theoretical molecular weight :

53 kDa

gene symbol :

CTSA

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (Catalog # ES005 ). The specific activity is 75 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P10619

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Cathepsin A/Lysosom Carboxypeptidase A, CF

USD :

443 USD

alt names :

beta-galactosidase 2, beta-galactosidase protective protein, Carboxypeptidase C, Carboxypeptidase L, cathepsin ANGBE, CTSA, EC 3.4.16, EC 3.4.16.5, GLB2, GSL, Lysosomal Carboxypeptidase A, lysosomal protective protein, PPCA, PPGBprotective protein for beta-galactosidase (galactosialidosis), Protective protein cathepsin A, Protective protein for beta-galactosidase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage