product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Cynomolgus Integrin alpha V beta 3 Protein, CF
catalog :
10426-AV-050
quantity :
50 ug
price :
491 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Bugatti A, Filippini F, Messali S, Giovanetti M, Ravelli C, Zani A, et al. The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells. Viruses. 2023;15: pubmed publisher
product information
master code :
10426-AV
SKU :
10426-AV-050
product name :
Recombinant Cynomolgus Integrin alpha V beta 3 Protein, CF
unit size :
50 ug
description :
The Recombinant Cynomolgus Integrin alpha V beta 3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Cynomolgus Integrin alpha V beta 3 Protein, CF has been validated for the following applications: Bioactivity.
target :
Integrin alpha V beta 3
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Cynomolgus Monkey
observed molecular weight :
105-160 kDa, under reducing conditions
theoretical molecular weight :
115 kDa (Integrin alpha V) 86 kDa (Integrin ▀3)
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Vitronectin (Catalog # 2308-VN ) is immobilized at 2 ╡g/mL (100 ╡L/well), Recombinant Cynomolgus Monkey Integrin alpha V▀3 (Catalog # 10426-AV) binds with an ED50 of 0.06-0.72 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
XP_005573729.1 (Integrin alpha V) XP_005584667.1 (Integrin ss3)
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey Integrin alpha V beta 3 protein Cynomolgus Monkey Integrin alpha V (Phe31-Val992) Accession # XP_005573729.1 His-Pro 2x GGGSGGGS-Acidic Tail 6-His tag Cynomolgus Monkey Integrin ss3 (Gly27-Asp718) Accession # XP_005584667.1 His-Pro 2x GGGSGGGS-Basic tail HA tag N-terminus C-terminus
source short :
CHO
USD :
491 USD
alt names :
antigen identified by monoclonal L230, CD51, CD51 antigen, integrin alpha-V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, Vitronectin receptor subunit alpha, VNRADKFZp686A08142
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.