Recombinant Mouse PDGF R beta Fc Chimera Protein, CF | R&D Systems 1042-PR-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse PDGF R beta Fc Chimera Protein, CF

catalog :

1042-PR-100

quantity :

100 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Strating E, Elias S, van Scharrenburg G, Luoto K, Verheem A, Borel Rinkes I, et al. Detection of Experimental Colorectal Peritoneal Metastases by a Novel PDGFRβ-Targeting Nanobody. Cancers (Basel). 2022;14: pubmed publisher
Delaney T, Morehouse C, Brohawn P, Groves C, Colonna M, Yao Y, et al. Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease. J Immunol. 2016;197:42-50 pubmed publisher
Tammela T, Saaristo A, Holopainen T, LyytikkÃ¤ J, Kotronen A, Pitkonen M, et al. Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation. Nat Med. 2007;13:1458-66 pubmed

product information

master code :

1042-PR

SKU :

1042-PR-100

product name :

Recombinant Mouse PDGF R beta Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse PDGF R beta Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse PDGF R beta Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

PDGF R beta

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

124 kDa, reducing conditions

theoretical molecular weight :

82.6 kDa (monomer)

gene symbol :

Pdgfrb

details of functionality :

Measured by its ability to inhibit the biological activity of PDGF-BB using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 6-48 ng/mL in the presence of 4 ng/mL recombinant human PDGF-BB.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P05622

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse PDGF R beta protein Mouse PDGF R▀ (Leu32-Lys530) Accession # P05622 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140b, CD140b antigen, EC 2.7.10, EC 2.7.10.1, JTK12, PDGFR, PDGFR1, PDGFRB, PDGF-R-beta, platelet-derived growth factor receptor, beta polypeptide

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage