Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF | R&D Systems 1041-TC-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF

catalog :

1041-TC-050

quantity :

50 ug

price :

432 USD

citations: 4

Reference
Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. J Immunol. 2015;194:542-52 pubmed publisher
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, et al. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement. PLoS ONE. 2014;9:e91857 pubmed publisher
Kimberley F, van der Sloot A, Guadagnoli M, Cameron K, Schneider P, Marquart J, et al. The design and characterization of receptor-selective APRIL variants. J Biol Chem. 2012;287:37434-46 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher

product information

master code :

1041-TC

SKU :

1041-TC-050

product name :

Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TACI/TNFRSF13B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

47 kDa, reducing conditions

theoretical molecular weight :

41 kDa (monomer)

gene symbol :

Tnfrsf13b

details of functionality :

Measured by its ability to inhibit BAFF-mediated proliferation of anti-IgM stimulated mouse B cells. Moore,áP.A. etáal . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider,áP. etáal . (1999) J. Exp. Med. 189 :1747. The ED50 for this effect is 3-10áng/mL in the presence of 2.5áng/mL of rhBAFF.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9ET35

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse TACI/TNFRSF13B protein Mouse TACI (Phe5 - Thr129) Accession # Q9ET35 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

CD267, CD267 antigen, CVID, CVID2, FLJ39942, MGC133214, TACIMGC39952, TNFRSF13B, TNFRSF14B, Transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B, tumor necrosis factor receptor superfamily, member 13B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.