product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF
catalog :
1041-TC-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. J Immunol. 2015;194:542-52 pubmed publisher
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, et al. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement. PLoS ONE. 2014;9:e91857 pubmed publisher
Kimberley F, van der Sloot A, Guadagnoli M, Cameron K, Schneider P, Marquart J, et al. The design and characterization of receptor-selective APRIL variants. J Biol Chem. 2012;287:37434-46 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher
product information
brand :
R&D Systems
master code :
1041-TC
SKU :
1041-TC-050
product name :
Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TACI/TNFRSF13B
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
47 kDa, reducing conditions
theoretical molecular weight :
41 kDa (monomer)
gene symbol :
Tnfrsf13b
details of functionality :
Measured by its ability to inhibit BAFF-mediated proliferation of anti-IgM stimulated mouse B cells. Moore,áP.A. etáal . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider,áP. etáal . (1999) J. Exp. Med. 189 :1747. The ED50 for this effect is 3-10áng/mL in the presence of 2.5áng/mL of rhBAFF.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9ET35
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF
USD :
432 USD
alt names :
CD267, CD267 antigen, CVID, CVID2, FLJ39942, MGC133214, TACIMGC39952, TNFRSF13B, TNFRSF14B, Transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B, tumor necrosis factor receptor superfamily, member 13B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.