product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ErbB3/Her3 His-tag Protein, CF
catalog :
10368-RB-050
quantity :
50 ug
price :
405 USD
more info or order :
image
image 1 :
R&D Systems 10368-RB-050 image 1
Recombinant Human ErbB3/Her3 His-tag Protein Bioactivity
product information
brand :
R&D Systems
master code :
10368-RB
SKU :
10368-RB-050
product name :
Recombinant Human ErbB3/Her3 His-tag Protein, CF
description :
The Recombinant Human ErbB3/Her3 His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human ErbB3/Her3 His-tag Protein, CF has been validated for the following applications: Bioactivity.
target :
ErbB3/Her3
category :
Proteins and Enzymes
unit sizes :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
73-83 kDa, under reducing conditions
theoretical molecular weight :
61 kDa
details of functionality :
Measured by its ability to inhibit the biological activity of Neuregulin-1-beta 1 on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.3-3 µg/mL in the presence of 10 ng/mL Recombinant Human NRG1-beta 1/HRG1-beta 1 Extracellular Domain (Catalog # 377-HB ).
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P21860.1
applications :
Bioactivity
source :
HEK293-derived Recombinant Human ErbB3/Her3 His-tag Protein, CF
USD :
405 USD
alt names :
c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.