product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Cynomolgus Monkey EGFR Fc Chimera Protein, CF
catalog :
10366-ER-100
quantity :
100 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
King L, Toffoli E, Veth M, Iglesias Guimarais V, Slot M, Amsen D, et al. A bispecific γδ T-cell engager targeting EGFR activates a potent Vγ9Vδ2 T cell-mediated immune response against EGFR-expressing tumors. Cancer Immunol Res. 2023;: pubmed publisher
product information
master code :
10366-ER
SKU :
10366-ER-100
product name :
Recombinant Cynomolgus Monkey EGFR Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Cynomolgus Monkey EGFR Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Cynomolgus Monkey EGFR Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
EGFR
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Cynomolgus Monkey
observed molecular weight :
110-130 kDa, under reducing conditions
theoretical molecular weight :
95 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey EGFR Fc Chimera (Catalog # 10366-ER) is immobilized at 2 ╡g/mL (100 ╡L/well), the concentration of Biotinylated Recombinant Human EGF that produces 50% of the optimal binding response is found to be approximately 4-20 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Cynomolgus Monkey EGFR Fc Chimera Protein Binding Activity
accessionNumbers :
XP_005549616.1
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey EGFR protein Cynomolgus Monkey EGFR (Leu25-Ser645) Accession # XP_005549616.1 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
CHO
USD :
468 USD
alt names :
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, EGF R, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ErbB, ErbB1, ERBB1PIG61, HER1, HER-1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.