product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Dectin-1/CLEC7A Fc Chimera Protein, CF
catalog :
10364-DC-050
quantity :
50 ug
price :
510 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Michaud E, Waeckel L, Gayet R, Goguyer Deschaumes R, Chanut B, Jospin F, et al. Alteration of microbiota antibody-mediated immune selection contributes to dysbiosis in inflammatory bowel diseases. EMBO Mol Med. 2022;14:e15386 pubmed publisher
product information
master code :
10364-DC
SKU :
10364-DC-050
product name :
Recombinant Human Dectin-1/CLEC7A Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human Dectin-1/CLEC7A Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human Dectin-1/CLEC7A Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Dectin-1/CLEC7A
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
54-64 kDa, under reducing conditions
theoretical molecular weight :
47 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Dectin-1/CLEC7A Fc Chimera (Catalog # 10364-DC) is immobilized at 0.25 ╡g/mL (100 ╡L/well), Biotinylated Laminarin (1, 3-beta-glucan) binds with an ED50 of 0.08-9.6 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human Dectin-1/CLEC7A Fc Chimera Protein Binding Activity
accessionNumbers :
Q9BXN2.1
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived human Dectin-1/CLEC7A protein MD Human IgG1 (Pro100-Lys330) IEGR Human Dectin-1/CLEC7A (Thr66-Met247) Accession # Q9BXN2.1 N-terminus C-terminus
source short :
HEK293
extended description :
HEK293 Expressed
USD :
510 USD
product details :
HEK293 Expressed
alt names :
Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.