Recombinant Human IL-19 Protein | R&D Systems 1035-IL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-19 Protein

catalog :

1035-IL-025

quantity :

25 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Tsaousi A, Witte E, Witte K, Röwert Huber H, Volk H, Sterry W, et al. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations. Mediators Inflamm. 2016;2016:4097574 pubmed
Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol. 2009;39:2779-88 pubmed publisher
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher
Sa S, Valdez P, Wu J, Jung K, Zhong F, Hall L, et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007;178:2229-40 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1035-IL

SKU :

1035-IL-025

product name :

Recombinant Human IL-19 Protein

Description :

The Recombinant Human IL-19 Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-19 Protein has been validated for the following applications: Bioactivity.

target :

IL-19

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

18 kDa (monomer)

gene symbol :

IL19

details of functionality :

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta . The ED50 for this effect is 0.2-1.2 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAN40906

applications :

Bioactivity

source :

E. coli-derived Recombinant Human IL-19 Protein

USD :

396 USD

alt names :

IL-10C, IL19, IL-19, interleukin 19, MDA1, melanoma differentiation associated protein-like protein, NG.1Melanoma differentiation-associated protein-like protein, ZMDA1interleukin-19

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage