product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MUC-1 Fc Chimera Protein, CF
catalog :
10332-MU-050
quantity :
50 ug
price :
482 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Kawano T, Englisch C, Hisada Y, Paul D, Archibald S, Grover S, et al. Mucin 1 and venous thrombosis in tumor-bearing mice and patients with cancer. Thromb Res. 2024;237:23-30 pubmed publisher
Pedram K, Laqtom N, Shon D, Di Spiezio A, Riley N, Saftig P, et al. Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals. Proc Natl Acad Sci U S A. 2022;119:e2117105119 pubmed publisher
product information
master code :
10332-MU
SKU :
10332-MU-050
product name :
Recombinant Human MUC-1 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human MUC-1 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human MUC-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
MUC-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
157 - 192 kDa, under reducing conditions.
theoretical molecular weight :
60 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human MUC-1 Fc Chimera (Catalog # 10332-MU) is immobilized at 1 ╡g/mL (100 ╡L/well), Recombinant Human Siglec-9 Fc Chimera (Catalog # 1139-SL ) binds with an ED50 of 0.2-1.4 ╡g/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human MUC-1 Fc Chimera Protein Binding Activity
accessionNumbers :
P15941.3
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived human MUC-1 protein Human MUC-1 (Ser24-Ser380) Accession # P15941.3 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
HEK293
USD :
482 USD
alt names :
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEM, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.