Recombinant Human CD25/IL-2R alpha His-tag Protein, CF | R&D Systems 10305-RL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD25/IL-2R alpha His-tag Protein, CF

catalog :

10305-RL-050

quantity :

50 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Kirschke S, Ogunsulire I, Selvakumar B, Schumacher N, Sezin T, Rose John S, et al. The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo. J Biol Chem. 2022;298:101910 pubmed publisher

image

image 1 :

Recombinant Human CD25/IL-2R alpha His-tag Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

10305-RL

SKU :

10305-RL-050

product name :

Recombinant Human CD25/IL-2R alpha His-tag Protein, CF

Description :

The Recombinant Human CD25/IL-2R alpha His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human CD25/IL-2R alpha His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

CD25/IL-2R alpha

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

35-43 kDa, under reducing conditions

theoretical molecular weight :

23 kDa

details of functionality :

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.15-1.2 µg/mL in the presence of 30 ng/mL of Recombinant Human IL-2 (Catalog # 202-IL )

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P01589

applications :

Bioactivity

source :

HEK293-derived Recombinant Human CD25/IL-2R alpha His-tag Protein

USD :

396 USD

alt names :

CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage