Bovine Fibronectin Protein, CF | R&D Systems 1030-FN-01M product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Bovine Fibronectin Protein, CF

catalog :

1030-FN-01M

quantity :

1 mg (also 5 mg)

price :

176 USD

citations: 15

Reference
Frey N, Ouologuem L, Blenninger J, Siow W, Thorn Seshold J, St xf6 ckl J, et al. Endolysosomal TRPML1 channel regulates cancer cell migration by altering intracellular trafficking of E-cadherin and β1-integrin. J Biol Chem. 2023;300:105581 pubmed publisher
Zheng C, Wei Y, Zhang Q, Sun M, Wang Y, Hou J, et al. Multiomics analyses reveal DARS1-AS1/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance. Sci Adv. 2023;9:eadf3984 pubmed publisher
Tobiume M, Mitsuhashi A, Saijo A, Ogino H, Afroj T, Ogawa H, et al. Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer. Oncol Lett. 2022;24:417 pubmed publisher
Marchese P, Lombardi M, Mantione M, Baccellieri D, Ferrara D, Chiesa R, et al. Confocal Blood Flow Videomicroscopy of Thrombus Formation over Human Arteries and Local Targeting of P2X7. Int J Mol Sci. 2021;22: pubmed publisher
Micali N, Kim S, Diaz Bustamante M, Stein O Brien G, Seo S, Shin J, et al. Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates. Cell Rep. 2020;31:107599 pubmed publisher
Ahn S, Maeng Y, Kim Y, Choe Y, Hwang H, Hyun Y. In vivo monitoring of dynamic interaction between neutrophil and human umbilical cord blood-derived mesenchymal stem cell in mouse liver during sepsis. Stem Cell Res Ther. 2020;11:44 pubmed publisher
Boukelmoune N, Chiu G, Kavelaars A, Heijnen C. Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin. Acta Neuropathol Commun. 2018;6:139 pubmed publisher
Vay S, Flitsch L, Rabenstein M, Rogall R, Blaschke S, Kleinhaus J, et al. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo. J Neuroinflammation. 2018;15:226 pubmed publisher
Yang J, Wu C, Stefănescu I, Horowitz A. Analysis of Retinoic Acid-induced Neural Differentiation of Mouse Embryonic Stem Cells in Two and Three-dimensional Embryoid Bodies. J Vis Exp. 2017;: pubmed publisher
Adepoju A, Micali N, Ogawa K, Hoeppner D, McKay R. FGF2 and insulin signaling converge to regulate cyclin D expression in multipotent neural stem cells. Stem Cells. 2014;32:770-8 pubmed publisher
Li Y, Bao Y, Song Z, Sun L, Wu P, Zhang Y, et al. The threonine protease activity of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation. PLoS ONE. 2012;7:e35030 pubmed publisher
Sasaki K, Pardee A, Okada H, Storkus W. IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit. Eur J Immunol. 2008;38:2865-73 pubmed publisher
Isakova I, Baker K, DuTreil M, Dufour J, Gaupp D, Phinney D. Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain. Stem Cells. 2007;25:3261-70 pubmed
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product information

master code :

1030-FN

SKU :

1030-FN-01M

product name :

Bovine Fibronectin Protein, CF

unit size :

1 mg (also 5 mg)

description :

The Bovine Fibronectin Protein, CF from R&D Systems is derived from Bovine Plasma. The Bovine Fibronectin Protein, CF has been validated for the following applications: Bioactivity.

target :

Fibronectin

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris-HCl, NaCl and Urea.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Bovine

gene symbol :

FN1

details of functionality :

Measured by its ability to support cell attachment and spreading when used as a substratum for cell culture. In this application, the recommended concentration for this effect is 1-5 ╡g/cm2. Fibronectin can also be added in the media to support cell spreading at a concentration of 0.5-50 ╡g/mL. Optimal concentration depends on cell type as well as the application or research objectives. Measured by the ability of the immobilized protein to support the adhesion of B16-F1 mouse melanoma cells. The ED50 for this effect is 10.0-100 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

top caption :

Staining of dopaminergic neurons with anti-tyrosine hydroxylase in green, anti-neuron-specific beta III tubulin Tuj1 in red and DAPI in blue

applications :

Bioactivity

source long :

Bovine plasma-derived Fibronectin protein

source short :

Bovine Plasma

USD :

176 USD

alt names :

CIG, ED-B, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF, SMDCF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. Thaw frozen material overnight at 2-8 ░C. Do not disturb the product during the initial thaw event. Avoid vortexing and excessive agitation of the product.