Recombinant Mouse TrkB Fc Chimera Protein, CF | R&D Systems 10266-TB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TrkB Fc Chimera Protein, CF

catalog :

10266-TB-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Ding X, Liao F, Su L, Yang X, Yang W, Ren Q, et al. Sciatic nerve block downregulates the BDNF pathway to alleviate the neonatal incision-induced exaggeration of incisional pain via decreasing microglial activation. Brain Behav Immun. 2022;105:204-224 pubmed publisher
Frick C, Fink S, Schmidbauer D, Rousset F, Eickhoff H, Tropitzsch A, et al. Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants. Brain Sci. 2020;10: pubmed publisher

product information

master code :

10266-TB

SKU :

10266-TB-050

product name :

Recombinant Mouse TrkB Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse TrkB Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TrkB Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TrkB

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

90-120 kDa, under reducing conditions

theoretical molecular weight :

72 kDa

details of functionality :

Measured by its ability to inhibit BDNF-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.05-0.4 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse TrkB Fc Chimera Protein Bioactivity

accessionNumbers :

P15209

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse TrkB protein Mouse TrkB (Cys32-His429) Accession # P15209 IEGRMDP Mouse IgG2a (Glu98-Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage