Recombinant Mouse IFN-gamma R1 Fc Chimera Protein, CF | R&D Systems 1026-GR-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IFN-gamma R1 Fc Chimera Protein, CF

catalog :

1026-GR-100

quantity :

100 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Nachbur U, Stafford C, Bankovacki A, Zhan Y, Lindqvist L, Fiil B, et al. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015;6:6442 pubmed publisher
Suzuki T, Ishii Watabe A, Tada M, Kobayashi T, Kanayasu Toyoda T, Kawanishi T, et al. Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR. J Immunol. 2010;184:1968-76 pubmed publisher

product information

master code :

1026-GR

SKU :

1026-GR-100

product name :

Recombinant Mouse IFN-gamma R1 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse IFN-gamma R1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IFN-gamma R1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

IFN-gamma R1/CD119

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

70-90 kDa, reducing conditions

theoretical molecular weight :

52.4 kDa (monomer)

gene symbol :

Ifngr1

details of functionality :

Measured by its ability to inhibit IFN-gamma -mediated anti-viral activity using L-929 mouse fibroblast cells. Meager, A. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 129. The ED50 for this effect is 6-36 ng/mL in the presence of 1 ng/mL of recombinant mouse IFN-gamma .

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q91Y85

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse IFN-gamma R1/CD119 protein Mouse IFN-gamma R1 (Ala26-Asp253) Accession # Q91Y85 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

AVP, type 2, CD119, CD119 antigen, FLJ45734, IFN-gamma receptor 1, IFNgammaR1, IFN-gamma-R1, IFNGR, IFN-gR1, IFNGR1, immune interferon receptor 1, interferon gamma receptor 1, interferon-gamma receptor alpha chain, type 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage