Recombinant Mouse IL-10 (Cys167Tyr) Protein, CF | R&D Systems 1023-ML-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-10 (Cys167Tyr) Protein, CF

catalog :

1023-ML-010/CF

quantity :

10 ug

price :

367 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, et al. Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock. Cytokine. 2012;60:266-70 pubmed publisher
Chen Y, Man K, Ling G, Chen Y, Sun B, Cheng Q, et al. A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-based immunotherapy: superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10. J Immunol. 2007;179:6009-15 pubmed

product information

master code :

1023-ML/CF

SKU :

1023-ML-010/CF

product name :

Recombinant Mouse IL-10 (Cys167Tyr) Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse IL-10 (Cys167Tyr) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse IL-10 (Cys167Tyr) Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-10

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

17 kDa, reducing conditions

theoretical molecular weight :

18.8 kDa (monomer)

gene symbol :

Il10

details of functionality :

Measured in a cell proliferation assay using MC/9-2 mouse mast cells. Thompson-Snipes, L.á et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 0.4-1.2 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_034678

applications :

Bioactivity

source long :

E. coli -derived mouse IL-10 protein Ser19-Ser178 (Cys167Tyr), with an N-terminal Met

source short :

E. coli

USD :

367 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage