Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF | R&D Systems 1020-RL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF

catalog :

1020-RL-050

quantity :

50 ug

price :

377 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
See K, Kadonosono T, Miyamoto K, Tsubaki T, Ota Y, Katsumi M, et al. Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display. Sci Rep. 2021;11:22098 pubmed publisher
Luissint A, Lutz P, Calderwood D, Couraud P, Bourdoulous S. JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation. J Cell Biol. 2008;183:1159-73 pubmed publisher

product information

brand :

R&D Systems

master code :

1020-RL

SKU :

1020-RL-050

product name :

Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF

description :

The Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD25/IL-2R alpha

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

65 kDa, reducing conditions

theoretical molecular weight :

48.3 kDa (monomer)

gene symbol :

IL2RA

details of functionality :

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.1-0.5 µg/mL in the presence of 30 ng/mL of recombinant human IL-2.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q5W007

applications :

Bioactivity

source :

NS0-derived Recombinant Human CD25/IL-2R alpha Fc Chimera Protein, CF

USD :

377

USD 2023 :

377 USD

alt names :

CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage