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company name :
R&D Systems
product type :
protein
product name :
Porcine TGF-beta 2 Protein
catalog :
102-B2-001
quantity :
1 ug
price :
493 USD
more info or order :
citations: 8
Reference
Shiraki N, Maruyama K, Hayashi R, Oguchi A, Murakawa Y, Katayama T, et al. PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids. Stem Cell Reports. 2022;17:221-230 pubmed publisher
Fujimoto T, Inoue Mochita M, Iraha S, Tanihara H, Inoue T. Suberoylanilide hydroxamic acid (SAHA) inhibits transforming growth factor-beta 2-induced increases in aqueous humor outflow resistance. J Biol Chem. 2021;297:101070 pubmed publisher
Yogi A, Rukhlova M, Charlebois C, Tian G, Stanimirovic D, Moreno M. Differentiation of Adipose-Derived Stem Cells into Vascular Smooth Muscle Cells for Tissue Engineering Applications. Biomedicines. 2021;9: pubmed publisher
Playford R, Weiser M, Marchbank T. Methods to improve efficacy of orally administered bioactive peptides using bovine colostrum as an exemplar. PLoS ONE. 2021;16:e0253422 pubmed publisher
Holvoet S, Perrot M, de Groot N, Prioult G, Mikogami T, Verhasselt V, et al. Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-β-Enriched Formula. Nutrients. 2019;11: pubmed publisher
Buijs J, Henriquez N, Van Overveld P, van der Horst G, Que I, Schwaninger R, et al. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res. 2007;67:8742-51 pubmed
Saika S, Kono Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, et al. Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice. Lab Invest. 2004;84:1245-58 pubmed
Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int J Dev Biol. 2003;47:15-29 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
102-B2
SKU :
102-B2-001
product name :
Porcine TGF-beta 2 Protein
Description :
The Porcine TGF-beta 2 Protein from R&D Systems is derived from Porcine Platelets. The Porcine TGF-beta 2 Protein has been validated for the following applications: Bioactivity.
target :
TGF-beta 2
category :
Proteins and Enzymes
unit size :
1 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Porcine
observed molecular weight :
12 kDa, reducing conditions
gene symbol :
TGFB2
details of functionality :
Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 0.03-0.18 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
applications :
Bioactivity
source :
Porcine Platelets
USD :
493 USD
alt names :
BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGFB2, TGFbeta 2, TGF-beta2, TGF-beta-2, transforming growth factor beta-2, transforming growth factor, beta 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.