Recombinant Human DLL4 Fc Chimera Protein, CF | R&D Systems 10185-D4-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human DLL4 Fc Chimera Protein, CF

catalog :

10185-D4-050

quantity :

50 ug

price :

373 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Sottoriva K, Paik N, White Z, Bandara T, Shao L, Sano T, et al. A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansion. JCI Insight. 2022;7: pubmed publisher
Schmidl B, Siegl M, Boxberg M, St xf6 gbauer F, Jira D, Winter C, et al. NOTCH1 Intracellular Domain and the Tumor Microenvironment as Prognostic Markers in HNSCC. Cancers (Basel). 2022;14: pubmed publisher
Wei K, Korsunsky I, Marshall J, Gao A, Watts G, Major T, et al. Notch signalling drives synovial fibroblast identity and arthritis pathology. Nature. 2020;582:259-264 pubmed publisher

image

image 1 :

Recombinant Human DLL4 Fc Chimera Protein Bioactivity

product information

brand :

R&D Systems

master code :

10185-D4

SKU :

10185-D4-050

product name :

Recombinant Human DLL4 Fc Chimera Protein, CF

description :

The Recombinant Human DLL4 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human DLL4 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

DLL4

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

88-98 kDa, under reducing conditions

theoretical molecular weight :

81 kDa

details of functionality :

Measured by the ability of the immobilized protein to enhance BMP-2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. Nobta, M. et al . (2005) J. Biol. Chem. 280 :15842. The ED50 fort his effect is 0.02-0.12 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9NR61

applications :

Bioactivity

source :

HEK293-derived Recombinant Human DLL4 Fc Chimera Protein, CF

USD :

367

USD 2023 :

373 USD

alt names :

delta 4, Delta 4 precursor, delta ligand 4, delta4, delta-like 4 (Drosophila), delta-like 4 homolog, delta-like 4 homolog (Drosophila), delta-like 4 protein, delta-like protein 4, Drosophila Delta homolog 4, hdelta2, MGC126344, notch ligand delta-2, notch ligand DLL4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage