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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF
catalog :
1006-UN-050
quantity :
50 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Boyé K, Geraldo L, Furtado J, Pibouin Fragner L, Poulet M, Kim D, et al. Endothelial Unc5B controls blood-brain barrier integrity. Nat Commun. 2022;13:1169 pubmed publisher
Brunet I, Gordon E, Han J, Cristofaro B, Broqueres You D, Liu C, et al. Netrin-1 controls sympathetic arterial innervation. J Clin Invest. 2014;124:3230-40 pubmed publisher
Ramkhelawon B, Hennessy E, Ménager M, Ray T, Sheedy F, Hutchison S, et al. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med. 2014;20:377-84 pubmed publisher
product information
brand :
R&D Systems
master code :
1006-UN
SKU :
1006-UN-050
product name :
Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
UNC5H2/UNC5B
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Rat
observed molecular weight :
85-90 kDa, reducing conditions
theoretical molecular weight :
65 kDa (monomer)
gene symbol :
Unc5b
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized rrUNC5H2/Fc Chimera at 5 ╡g/mL (100 ╡L/well) can bind rcNetrin-1 with a linear range of 6-400áng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O08722
applications :
Binding Activity
source :
NS0-derived Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF
USD :
468 USD
alt names :
p53RDL1, p53-regulated receptor for death and life protein 1, Protein unc-5 homolog 2, Protein unc-5 homolog B, transmembrane receptor Unc5H2, unc5 (C.elegans homolog) b, unc-5 homolog 2, unc-5 homolog B (C. elegans), UNC5B, UNC5H2netrin receptor UNC5B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.