Recombinant Mouse ST2/IL-33R Fc Chimera Protein, CF | R&D Systems 1004-MR-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ST2/IL-33R Fc Chimera Protein, CF

catalog :

1004-MR-050

quantity :

50 ug

price :

432 USD

citations: 10

Reference
Ikehata Y, Oshima E, Hayashi Y, Tanaka Y, Sato H, Hitomi S, et al. Fibroblast-derived IL-33 exacerbates orofacial neuropathic pain via the activation of TRPA1 in trigeminal ganglion neurons. Brain Behav Immun. 2025;123:982-996 pubmed publisher
Faustino L, Griffith J, Rahimi R, Nepal K, Hamilos D, CHO J, et al. Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung. Nat Immunol. 2020;21:1371-1383 pubmed publisher
Frisbee A, Saleh M, Young M, Leslie J, Simpson M, Abhyankar M, et al. IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection. Nat Commun. 2019;10:2712 pubmed publisher
Fu A, Hung K, Yuen M, Zhou X, Mak D, Chan I, et al. IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline. Proc Natl Acad Sci U S A. 2016;113:E2705-13 pubmed publisher
Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, et al. Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. J Immunol. 2015;195:3537-45 pubmed publisher
Seeber S, Ros F, Thorey I, Tiefenthaler G, Kaluza K, Lifke V, et al. A robust high throughput platform to generate functional recombinant monoclonal antibodies using rabbit B cells from peripheral blood. PLoS ONE. 2014;9:e86184 pubmed publisher
Williams J, Tjota M, Clay B, Vander Lugt B, Bandukwala H, Hrusch C, et al. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nat Commun. 2013;4:2990 pubmed publisher
Drube S, Heink S, Walter S, Löhn T, Grusser M, Gerbaulet A, et al. The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells. Blood. 2010;115:3899-906 pubmed publisher
Ali S, Huber M, Kollewe C, Bischoff S, Falk W, Martin M. IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proc Natl Acad Sci U S A. 2007;104:18660-5 pubmed
Chackerian A, Oldham E, Murphy E, Schmitz J, Pflanz S, Kastelein R. IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. J Immunol. 2007;179:2551-5 pubmed

product information

master code :

1004-MR

SKU :

1004-MR-050

product name :

Recombinant Mouse ST2/IL-33R Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse ST2/IL-33R Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse ST2/IL-33R Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

ST2/IL-33R

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

73 kDa, reducing conditions

theoretical molecular weight :

63 kDa (monomer)

gene symbol :

Il1rl1

details of functionality :

Measured by its ability to bind Recombinant Mouse IL-33 (Catalog # 3626-ML ) in a functional ELISA with an estimated KD 50 nM. Schmitz, J. et al . (2005) Immunity 23 :479.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P14719

applications :

Binding Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse ST2/IL-33R protein Mouse ST2 (Ser27-Ser342) Accession # P14719 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

DER4, DER4ST2growth stimulation-expressed, FIT-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33 R, IL33R, IL-33R, interleukin 1 receptor-like 1, interleukin 1 receptor-related protein, interleukin-1 receptor-like 1, Ly84, MGC32623, Protein ST2, ST2L, ST2V, T1, T1homolog of mouse growth stimulation-expressed

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.