product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TGF-beta RII Isoform 2 Fc Chimera, CF
catalog :
1003-RT-050
quantity :
50 ug
price :
480 USD
more info or order :
citations: 3
Reference
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed publisher
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher
Godfrey W, Spoden D, Ge Y, Baker S, Liu B, Levine B, et al. Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood. 2005;105:750-8 pubmed
product information
brand :
R&D Systems
master code :
1003-RT
SKU :
1003-RT-050
product name :
Recombinant Human TGF-beta RII Isoform 2 Fc Chimera, CF
unit size :
50 ug
seo description :
The Recombinant Human TGF-beta RII Isoform 2 Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human TGF-beta RII Isoform 2 Fc Chimera, CF has been validated for the following applications: Bioactivity.
target :
TGF-beta RII
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
65-75 kDa, reducing conditions
theoretical molecular weight :
45 kDa (monomer)
gene symbol :
TGFBR2
details of functionality :
Measured by its ability to inhibit TGF┐▀1 activity on HT-2 mouse T cells. Tsang,áM. etáal . (1995) Cytokine 7 :389. The ED50 for this effect is 1-3 ng/mL in the presence of 0.1 ng/mL of recombinant human TGF┐▀1.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_001020018
applications :
Bioactivity
source :
NS0-derived Recombinant Human TGF-beta RII Isoform 2 Fc Chimera, CF
USD :
480 USD
alt names :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.