Anti-Collagen V Alpha-1 Chain N-propeptide-NC2 domain Antibody | QED Bioscience 90008 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Collagen V Alpha-1 Chain N-propeptide-NC2 domain Antibody

catalog :

90008

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

18G5

The same clone is also sold as:

OriGene: AM10158PU-N

reactivity :

human

product information

CATALOG NUMBER :

90008

PRODUCT NAME :

Anti-Collagen V Alpha-1 Chain N-propeptide-NC2 domain Antibody

NAME+SKU :

Anti-Collagen V Alpha-1 Chain N-propeptide-NC2 domain Antibody (90008)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Collagen V Alpha-1 Chain (NC2 domain) Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Collagen V Alpha-1 Chain (NC2 domain)

SPECIES REACTIVITY :

Human

TARGET NAME :

Collagen V Alpha-1 Chain N-propeptide-NC2 domain

UNIPROT :

P20908

LOCATION :

Secreted, extracellular space, extracellular matrix

PROTEIN NAME :

Collagen alpha-1(V) chain

GENE NAME :

COL5A1

CLONALITY :

Monoclonal

FORM :

Lyophilized

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

348.6

SKU SIZE 1 :

90008

APPLICATIONS :

WB, IHC

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-5ug/ml. Immunohistochemistry: Formalin-fixed, paraffin-embedded tissue, heat-induced antigen retrieval. Use at 1-10ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their applications.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

18G5

IMMUNOGEN :

Recombinant human collagen V alpha-1 chain N fragment.

RESEARCH AREA :

Cell adhesion

FORMULATION :

Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.

BUFFER :

Tris Buffer

TARGET BACKGROUND :

Collagen V alpha-1chain is a protein that in humans is encoded by the COL5A1 gene. This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.

FUNCTION :

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.

STORAGE CONDITION :

This product is stable for at least one (1) year at -20C to -70C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.

SPECIFICITY :

This antibody reacts with human collagen V alpha-1 chain propeptide. The epitope recognized is in the COL2- NC2 region. Cross-reactivity with mouse is predicted based on sequence homology.

Image Name_1 :

qed-bioscience-anti-collagen-v-alpha-1-chain-n-propeptide-nc2-domain-antibody-90008-1.jpg

Applications 1 :

IHC