Anti-CD73/5'Nucleotidase Antibody | QED Bioscience 90006 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-CD73/5'Nucleotidase Antibody

catalog :

90006

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10f1

reactivity :

human

product information

CATALOG NUMBER :

90006

PRODUCT NAME :

Anti-CD73/5'Nucleotidase Antibody

NAME+SKU :

Anti-CD73/5'Nucleotidase Antibody (90006)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-CD73/5'-Nucleotidase Mouse Monoclonal Antibody

SPECIFICITY SHORT :

CD73/5'-Nucleotidase

SPECIES REACTIVITY :

Human

TARGET NAME :

CD73/5'Nucleotidase

UNIPROT :

P21589

LOCATION :

Cell membrane; Lipid-anchor, GPI-anchor.

PROTEIN NAME :

5'-nucleotidase

ALTERNATIVE NAMES :

5'-NT, EC 3.1.3.5, Ecto-5'-nucleotidase, CD antigen CD73

GENE NAME :

NT5E

CLONALITY :

Monoclonal

FORM :

Lyophilized

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

348.6

SKU SIZE 1 :

90006

APPLICATIONS :

WB, IHC, ELISA

APPLICATION INSTRUCTIONS :

ELISA: use at 1-10ug/ml. Immunoblotting: use at 1-5ug/ml. A band of ~63kDa is detected. Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their applications.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

10f1

IMMUNOGEN :

Recombinant 5â€™-nucleotidase (5â€™-NT). Accession no. P21589.

RESEARCH AREA :

Enzymes

FORMULATION :

Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.

BUFFER :

Tris Buffer

TARGET BACKGROUND :

5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (Cluster of Differentiation 73), is an enzyme that in humans is encoded by the NT5E gene. CD73 converts AMP to adenosine. This enzyme consists of a dimer of 2 identical 70-kDa subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. A deficiency of NT5 occurs in a variety of immunodeficiency diseases

FUNCTION :

Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. {PubMed:21933152}.

STORAGE CONDITION :

This antibody is stable for 1 month at 4°C or one year at -20°C. Avoid multiple freeze-thaw cycles.

SPECIFICITY :

This antibody reacts with human 5â€™-NT.