Anti-PSE1/Ku Protein Antibody | QED Bioscience 70104 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-PSE1/Ku Protein Antibody

catalog :

70104

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N3H10

The same clone is also sold as:

Santa Cruz Biotechnology: sc-56129 HRP, sc-56129, sc-56129 AC

reactivity :

human, mouse

product information

CATALOG NUMBER :

70104

PRODUCT NAME :

Anti-PSE1/Ku Protein Antibody

NAME+SKU :

Anti-PSE1/Ku Protein Antibody (70104)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-PSE1/Ku Protein Mouse Monoclonal Antibody

SPECIFICITY SHORT :

PSE1/Ku Protein

SPECIES REACTIVITY :

Human

TARGET NAME :

PSE1/Ku Protein

UNIPROT :

P23475

LOCATION :

Nucleus , Chromosome

PROTEIN NAME :

X-ray repair cross-complementing protein 6

ALTERNATIVE NAMES :

EC 3.6.4.-, EC 4.2.99.-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP/AP lyase Ku70, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Ku autoantigen protein p70 homolog, Ku70

GENE NAME :

Xrcc6

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

200 ug

DISTIRBUTOR PRICE :

285.6

SKU SIZE 1 :

70104

APPLICATIONS :

WB, Gel Shift

APPLICATION INSTRUCTIONS :

These antibodies work well in Western blot and electrophoretic mobility (gel shift) assays for identifying PSE1 or Ku. They may be used to immuno-deplete Ku protein from protein mixtures prior to specific DNA affinity chromatography.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG2b

CLONE ID :

N3H10

IMMUNOGEN :

Proximal sequence element (PSE1) of the human U1 small nuclear RNA extracted from human placenta.

RESEARCH AREA :

Protein Transcription

FORMULATION :

PBS, pH 7.4.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

FUNCTION :

Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA (By similarity). Required for double-strand break repair and V(D)J rUniProtKB:P12956, PubMed:12145306}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

These antibodies are stable for at least one (1) year at -20 C to -70 C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

SPECIFICITY :

70104 recognizes the small beta subunit (~70 kDa) and 70105 recognizes the large alpha subunit (~80-90 kDa) of placental PSE1 and human Ku in solution and when bound to DNA.