Anti-Neuroligin-3 Antibody | QED Bioscience 56552 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Neuroligin-3 Antibody

catalog :

56552

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S110-29

The same clone is also sold as:

Novus Biologicals: NBP2-42200
Rockland Immunochemicals: 200-363-W83, 200-366-W83, 200-367-W83, 200-360-W83, 200-303-W83, 200-352-W83, 200-365-W83, 200-301-W83, 200-355-W83, 200-361-W83, 200-357-W83, 200-362-W83, 200-306-W83, 200-326-W83, 200-305-W83, 200-302-W83, 200-308-W83, 200-358-W83
OriGene: AM60053PU-N

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56552

PRODUCT NAME :

Anti-Neuroligin-3 Antibody

NAME+SKU :

Anti-Neuroligin-3 Antibody (56552)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Neuroligin-3 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Neuroligin-3

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Neuroligin-3

UNIPROT :

Q62889

LOCATION :

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.

PROTEIN NAME :

Neuroligin-3

ALTERNATIVE NAMES :

Gliotactin homolog

GENE NAME :

Nlgn3

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56552

APPLICATIONS :

WB, IF

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-5ug/ml. A band of ~110kDa is detected. Immunofluorescence: use at 10ug/ml. These are recommended concentrations. Endusers should determine optimal concentrations for their application.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

S110-29

IMMUNOGEN :

Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.1% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

FUNCTION :

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

This product is stable for at least one (1) year at -20C.

SPECIFICITY :

This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.

Image Name_1 :

qed-bioscience-anti-neuroligin-3-antibody-56552-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-neuroligin-3-antibody-56552-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-neuroligin-3-antibody-56552-3.png

Applications 3 :

Western Blot