This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
QED Bioscience
product type :
antibody
product name :
Anti-Neuroligin-1 Antibody
catalog :
56551
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S97A-31

The same clone is also sold as:
reactivity :
human, mouse, rat
product information
CATALOG NUMBER :
56551
PRODUCT NAME :
Anti-Neuroligin-1 Antibody
NAME+SKU :
Anti-Neuroligin-1 Antibody (56551)
PRODUCT _TYPE :
Antibody
DESCRIPTION :
Anti-Neuroligin-1 Mouse Monoclonal Antibody
SPECIFICITY SHORT :
Neuroligin-1
SPECIES REACTIVITY :
Human, mouse, rat
TARGET NAME :
Neuroligin-1
UNIPROT :
Q62765
LOCATION :
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density , Cell junction, synapse, synaptic cleft , Cell junction, synapse, synaptic cell membrane
PROTEIN NAME :
Neuroligin-1
ALTERNATIVE NAMES :
Neuroligin I
GENE NAME :
Nlgn1
CLONALITY :
Monoclonal
FORM :
Liquid
CONCENTRATION :
1.0 mg/mL
SIZE 1 :
100 ug
DISTIRBUTOR PRICE :
305.2
SKU SIZE 1 :
56551
APPLICATIONS :
WB, IF
APPLICATION INSTRUCTIONS :
Immunoblotting: use at 1-5ug/ml. A band of ~120kDa is detected. Immunofluorescence: use at 10ug/ml. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.
HOST :
Mouse
FORMAT :
Purified
PURIFICATION :
Purified by Protein G affinity chromatography.
ISOTYPE :
IgG1
CLONE ID :
S97A-31
IMMUNOGEN :
Fusion protein corresponding to aa 718-843 (cytoplasmic C-terminus) of rat Neuroligin- 1, accession no. Q62765). This sequence is 99
RESEARCH AREA :
Neuroscience
FORMULATION :
PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
BUFFER :
Phosphate Buffered Saline
BUFFER PH :
pH 7.4
BUFFER ANTI-MICROBIAL :
0.1% Sodium Azide
BUFFER CRYOPRESERVATIVE :
50% Glycerol
TARGET BACKGROUND :
Neuroligin-1 is a neuronal cell surface protein and member of the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses, it participates in regulation of synaptic plasticity, and it is important in the development of long- term memory in adult mammalian amygdala. It’s participation in cell-cell interactions may occur through assembly of intracellular junctions by binding of beta-neurexins. In nervous system tissue, Neuroligin-1 is observed primarily in neurons and in the spinal cord.
FUNCTION :
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep (By similarity). The protein is involved in nervous system development. {UniProtKB:Q99K10, PubMed:15620359, PubMed:9325340}.
DILUTION INSTRUCTIONS :
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE CONDITION :
This product is stable for at least one (1) year at -20C.
SPECIFICITY :
This antibody recognizes human, mouse, and rat Neuroligin-1. It does not cross- react with other Neuroligins.
Image Name_1 :
qed-bioscience-anti-neuroligin-1-antibody-56551-1.png
Applications 1 :
ICC
Image Name_2 :
qed-bioscience-anti-neuroligin-1-antibody-56551-2.png
Applications 2 :
ICC
Image Name_3 :
qed-bioscience-anti-neuroligin-1-antibody-56551-3.png
Applications 3 :
Western Blot
company information
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
headquarters: United States