Anti-PINK1 Antibody | QED Bioscience 56548 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-PINK1 Antibody

catalog :

56548

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S4-15

The same clone is also sold as:

Rockland Immunochemicals: 200-326-W64, 200-305-W64, 200-361-W64, 200-357-W64, 200-360-W64, 200-365-W64, 200-358-W64, 200-301-W64, 200-302-W64, 200-306-W64, 200-352-W64, 200-362-W64, 200-367-W64, 200-308-W64, 200-303-W64, 200-363-W64, 200-366-W64, 200-355-W64

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56548

PRODUCT NAME :

Anti-PINK1 Antibody

NAME+SKU :

Anti-PINK1 Antibody (56548)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-PINK1 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

PINK1

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

PINK1

UNIPROT :

Q9BXM7.1

PROTEIN NAME :

Serine/threonine-protein kinase PINK1, mitochondrial

GENE NAME :

PINK1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56548

APPLICATIONS :

WB, IF

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-5ug/ml. A band of ~50kDa is detected. Immunofluorescence: use at 10ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their application.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

S4-15

IMMUNOGEN :

Fusion protein corresponding to aa 112-496 (cytoplasmic C-terminus) of human PINK1. This sequence is 82

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.1% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

PINK1 (PTEN-induced putative kinase 1) is a mitochondrial serine/threonine kinase that maintains mitochondrial function and integrity, provides protection against mitochondrial dysfunction during cellular stress, and is involved in the clearance of damaged mitochondria via selective autophagy. PINK1 is synthesized as a 63kDa protein which undergoes proteolytic processing to yield two cleaved forms, ~55kDa and ~42kDa. PINK1 may be localized to the outer mitochondrial membrane with its kinase domain facing the cytosol which would explain the observed physical interaction between PINK1 and cytosolic E3 ubiquitin ligase Parkin.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freezing and thawing.

SPECIFICITY :

This antibody recognizes human, mouse, and rat PINK1.

Image Name_1 :

qed-bioscience-anti-pink1-antibody-56548-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-pink1-antibody-56548-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-pink1-antibody-56548-3.png

Applications 3 :

Western Blot