Anti-AMIGO-1 Antibody | QED Bioscience 56530 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-AMIGO-1 Antibody

catalog :

56530

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S86-36

The same clone is also sold as:

OriGene: TA326398
Novus Biologicals: NBP2-22413

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56530

PRODUCT NAME :

Anti-AMIGO-1 Antibody

NAME+SKU :

Anti-AMIGO-1 Antibody (56530)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-AMIGO-1 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

AMIGO-1

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

AMIGO-1

UNIPROT :

Q86WK6

LOCATION :

Cell membrane , Perikaryon , Cell projection, dendrite , Cell projection, axon

PROTEIN NAME :

Amphoterin-induced protein 1

ALTERNATIVE NAMES :

AMIGO-1, Alivin-2

GENE NAME :

AMIGO1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56530

APPLICATIONS :

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1ug/ml. Predicted molecular weight is ~60-80kDa depending on maturity/glycosylation. Positive Control: rat brain lysate. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

S86-36

IMMUNOGEN :

Fusion protein corresponding to aa 554-574, the cytoplasmic C- terminus, of human AMIGO-1 (accession no.Q86WK6).

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, (also designated Alivin2) promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons.

FUNCTION :

Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. {UniProtKB:Q80ZD7, UniProtKB:Q80ZD8}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freeze- thaw cycles.

SPECIFICITY :

This antibody recognizes human, mouse and rat AMIGO-1. It does not cross- react with AMIGO-2 or AMIGO-3.

Image Name_1 :

qed-bioscience-anti-amigo-1-antibody-56530-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-amigo-1-antibody-56530-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-amigo-1-antibody-56530-3.png

Applications 3 :

Western Blot