Anti-SNAT1 Neurotransmitter Transporter Antibody | QED Bioscience 56522 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-SNAT1 Neurotransmitter Transporter Antibody

catalog :

56522

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S104-32

The same clone is also sold as:

Novus Biologicals: NBP2-59311
OriGene: TA326593

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56522

PRODUCT NAME :

Anti-SNAT1 Neurotransmitter Transporter Antibody

NAME+SKU :

Anti-SNAT1 Neurotransmitter Transporter Antibody (56522)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-SNAT1 Neurotransmitter Transporter Mouse Monoclonal Antibody

SPECIFICITY SHORT :

SNAT1 Neurotransmitter Transporter

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

SNAT1 Neurotransmitter Transporter

UNIPROT :

Q9JM15

LOCATION :

Cell membrane

PROTEIN NAME :

Sodium-coupled neutral amino acid transporter 1

ALTERNATIVE NAMES :

Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System A transporter 2, System N amino acid transporter 1

GENE NAME :

Slc38a1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56522

APPLICATIONS :

WB, IHC

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-2ug/ml. A band of ~50kDa is detected. Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their applications. Positive control: Rat neocortical neurons cultured under amino acid starvation conditions.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

S104-32

IMMUNOGEN :

Fusion protein corresponding to aa 1-63 (cytoplasmic N-terminus) of rat SNAT1 (accession no. NP_620187.1).

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

The sodium-coupled neutral amino acid transporters (SNAT) include System A subtypes SNAT1, SNAT2, and SNAT4 and System N subtypes SNAT3 and SNAT5. These transporters are essential for uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT1 is responsible for transport of glutamine and may be involved in the generation of glutamate in the retina. SNAT1 is found in heart, brain, and placenta, and expression levels are high in certain neuronal populations in the central nervous system.

FUNCTION :

Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. {PubMed:10660562, PubMed:11692272, PubMed:11756489, PubMed:12684517}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This product is stable for at least 1 year at -20C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

SPECIFICITY :

This antibody recognizes human, mouse, and rat SNAT1.

Image Name_1 :

qed-bioscience-anti-snat1-neurotransmitter-transporter-antibody-56522-1.png

Applications 1 :

Western Blot

Image Name_2 :

qed-bioscience-anti-snat1-neurotransmitter-transporter-antibody-56522-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-snat1-neurotransmitter-transporter-antibody-56522-3.png

Applications 3 :

ICC