Anti-Copper-Transporting ATPase2 Antibody | QED Bioscience 56517 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Copper-Transporting ATPase2 Antibody

catalog :

56517

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S62-29

The same clone is also sold as:

Abcam: ab240880
OriGene: TA326438
Novus Biologicals: NBP2-59375

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56517

PRODUCT NAME :

Anti-Copper-Transporting ATPase2 Antibody

NAME+SKU :

Anti-Copper-Transporting ATPase2 Antibody (56517)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Copper-Transporting ATPase2 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Copper-Transporting ATPase2

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Copper-Transporting ATPase2

UNIPROT :

B7ZLR4

PROTEIN NAME :

P-type Cu(+) transporter

GENE NAME :

ATP7B

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56517

APPLICATIONS :

WB, IHC

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-2ug/ml. A band of ~160kDa is detected. Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their applications. Positive control: rat brain membranes.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

S62-29

IMMUNOGEN :

Synthetic peptide correspond- ing to aa 3-21 (cytoplasmic N-terminus) of human Copper-Transporting ATPase2. (accession no. NP_000044.2).

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from cells. ATP7b (also known as Copper-Transporting ATPase2) transports copper in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene: A is found in the liver, kidney and brain, the shorter form B is found in brain, and the third isoform, known as WND/140KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilsonâ€™s disease, an inherited disorder causing copper poisoning in the brain and liver.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This product is stable for at least 1 year at -20C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

SPECIFICITY :

This antibody recognizes human, mouse, and rat Copper-Transporting ATPase2.

Image Name_1 :

qed-bioscience-anti-copper-transporting-atpase2-antibody-56517-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-copper-transporting-atpase2-antibody-56517-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-copper-transporting-atpase2-antibody-56517-3.png

Applications 3 :

Western Blot