Anti-VGlut2 Transporter Antibody | QED Bioscience 56515 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-VGlut2 Transporter Antibody

catalog :

56515

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S29-29

The same clone is also sold as:

OriGene: TA326590
Novus Biologicals: NBP2-59330

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

56515

PRODUCT NAME :

Anti-VGlut2 Transporter Antibody

NAME+SKU :

Anti-VGlut2 Transporter Antibody (56515)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-VGlut2 Transporter Mouse Monoclonal Antibody

SPECIFICITY SHORT :

VGlut2 Transporter

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

VGlut2 Transporter

UNIPROT :

Q9JI12

LOCATION :

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane , Cell junction, synapse, synaptosome

PROTEIN NAME :

Vesicular glutamate transporter 2

ALTERNATIVE NAMES :

VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6

GENE NAME :

Slc17a6

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56515

APPLICATIONS :

WB, IHC

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-2ug/ml. A band of ~60kDa is detected. Immunohistochemistry: use at 1-5ug/ml. These are recommended concentrations. Enduser should determine optimal concentrations for their applications. Positive control: rat brain lysate.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

S29-29

IMMUNOGEN :

Fusion protein corresponding to aa 501-582 (cytoplasmic C-terminus) of rat VGlut2 (accession no. NP_445879).

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

The ATP-dependent, chloride-sensitive vesicular glutamate transporters include VGlut1, VGlut2, and VGlut3. VGlut1 and VGlut2 are expressed in brain in a complementary fashion. VGlut1 is expressed in the telencephalic regions whereas VGlut2 is expressed in the lower brainstem and diencephalic regions. VGlut3 is expressed in a small number of neurons in the striatum, hippocampus, cerebral cortex, and raphe nuclei. Pancreatic alpha and beta cells express VGlut1 and VGlut2 in response to glucose concentrations.

FUNCTION :

Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:11551935, PubMed:11698619, PubMed:11698620, PubMed:11502256, PubMed:17046815, PubMed:18080752). May also mediate the transport of inorganic phosphate (PubMed:17046815). Involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity). May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas (PubMed:11551935). {UniProtKB:Q8BLE7, PubMed:11502256, PubMed:11551935, PubMed:11698619, PubMed:11698620, PubMed:17046815, PubMed:18080752}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This product is stable for at least 1 year at -20C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

SPECIFICITY :

This antibody recognizes human, mouse, and rat VGlut2.

Image Name_1 :

qed-bioscience-anti-vglut2-transporter-antibody-56515-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-vglut2-transporter-antibody-56515-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-vglut2-transporter-antibody-56515-3.png

Applications 3 :

Western Blot