Anti-EndoPDI Antibody | QED Bioscience 56458 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-EndoPDI Antibody

catalog :

56458

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E7/7

The same clone is also sold as:

OriGene: TA326409
StressMarq Biosciences: SMC-204
Invitrogen: MA5-45305, MA5-45307, MA5-45306

reactivity :

human

product information

CATALOG NUMBER :

56458

PRODUCT NAME :

Anti-EndoPDI Antibody

NAME+SKU :

Anti-EndoPDI Antibody (56458)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-EndoPDI Mouse Monoclonal Antibody

SPECIFICITY SHORT :

EndoPDI

SPECIES REACTIVITY :

Human

TARGET NAME :

EndoPDI

UNIPROT :

Q8NBS9

LOCATION :

Endoplasmic reticulum lumen

PROTEIN NAME :

Thioredoxin domain-containing protein 5

ALTERNATIVE NAMES :

Endoplasmic reticulum resident protein 46, ER protein 46, ERp46, Thioredoxin-like protein p46

GENE NAME :

TXNDC5

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

56458

APPLICATIONS :

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1ug/ml. A band of ~48kDa is detected. Positive control: heat-shocked HeLa cell lysate. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG2a

CLONE ID :

2E7/7

IMMUNOGEN :

Synthetic peptide corresponding to aa 52-63 (ADGEDGQDPHSK) of human EndoPDI (accession no. NP_001139021).

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Endothelial protein disulfide isomerase (EndoPDI) is a thiredoxin member of the protein disulfide isomerase family of chaperones. This enzyme is localized in the endoplasmic reticulum in primary endothelial cells but colocalizes with nucleoli in the nuclei of breast, colon, and kidney cancer cells. EndoPDI mRNA and protein expression is iduced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia.

FUNCTION :

Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). {ECO:0000250}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C.

SPECIFICITY :

This antibody recognizes human EndoPDI.

Image Name_1 :

qed-bioscience-anti-endopdi-antibody-56458-1.png

Applications 1 :

ICC