Anti-CaMKII Antibody | QED Bioscience 56370-200 product information

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product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-CaMKII Antibody

catalog :

56370-200

quantity :

200 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken, bovine

product information

CATALOG NUMBER :

56370-200

PRODUCT NAME :

Anti-CaMKII Antibody

NAME+SKU :

Anti-CaMKII Antibody (56370-200)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-CaMKII Rabbit Polyclonal Antibody

SPECIFICITY SHORT :

CaMKII

SPECIES REACTIVITY :

Human, mouse, rat, bovine, hamster, guinea pig, chicken, rabbit

TARGET NAME :

CaMKII

PROTEIN NAME :

Calcium/calmodulin-dependent protein kinase type II subunit alpha

ALTERNATIVE NAMES :

CaM kinase II subunit alpha, CaMK-II subunit alpha, EC 2.7.11.17

GENE NAME :

CAMK2A

ACCESSION NUMBER :

NP_741960.1

CLONALITY :

Polyclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

200 ug

DISTIRBUTOR PRICE :

428.4

SKU SIZE 1 :

56370-200

APPLICATIONS :

APPLICATION INSTRUCTIONS :

Immunoblotting: Use at 1-5ug/ml. A band of ~50-60 kDa is detected. Immunohistochemistry: use at 1-10ug/ml. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.

HOST :

Rabbit

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

IMMUNOGEN :

Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH.

RESEARCH AREA :

Enzymes

FORMULATION :

PBS, 50% glycerol, 0.09% sodium azide.

BUFFER :

Phosphate Buffered Saline

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimerâ€™s disease, Angelman syndrome, and heart arrhythmia.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Store in appropriate aliquots to avoid multiple freeze/thaw cycles.

Image Name_1 :

qed-bioscience-anti-camkii-antibody-56370-1.jpg

Applications 1 :

Image Name_2 :

qed-bioscience-anti-camkii-antibody-56370-2.jpg

Applications 2 :

IHC