This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
QED Bioscience
product type :
antibody
product name :
Anti-p95/Nibrin Antibody
catalog :
56249
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D7

The same clone is also sold as:
reactivity :
human
product information
CATALOG NUMBER :
56249
PRODUCT NAME :
Anti-p95/Nibrin Antibody
NAME+SKU :
Anti-p95/Nibrin Antibody (56249)
PRODUCT _TYPE :
Antibody
DESCRIPTION :
Anti-p95 Mouse Monoclonal Antibody
SPECIFICITY SHORT :
p95
SPECIES REACTIVITY :
Human
TARGET NAME :
p95/Nibrin
UNIPROT :
O60934
LOCATION :
Nucleus , Nucleus, PML body , Chromosome, telomere , Chromosome
PROTEIN NAME :
Nibrin
ALTERNATIVE NAMES :
Cell cycle regulatory protein p95, Nijmegen breakage syndrome protein 1
GENE NAME :
NBN
CLONALITY :
Monoclonal
FORM :
Liquid
CONCENTRATION :
Lot Specific
SIZE 1 :
100 ug
DISTIRBUTOR PRICE :
322.7
SKU SIZE 1 :
56249
APPLICATIONS :
WB, IP
APPLICATION INSTRUCTIONS :
Immunoblotting, immunoprecipitation:: use at 1-2 ug/ml. In immunoblots, a band of 95 kD is detected. Positive controls: MCF-7, HeLa, or Raji cells.
HOST :
Mouse
FORMAT :
Purified
PURIFICATION :
Purified by Protein G affinity chromatography.
ISOTYPE :
IgG1
CLONE ID :
1D7
IMMUNOGEN :
Fusion protein containing the complete coding region of human p95/nibrin expressed in E. coli.
RESEARCH AREA :
Cancer research
FORMULATION :
PBS, pH 7.4.
BUFFER :
Phosphate Buffered Saline
BUFFER PH :
pH 7.4
FUNCTION :
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA rPubMed:10888888, PubMed:15616588, PubMed:19759395, PubMed:23762398, PubMed:26438602, PubMed:9705271}.
DILUTION INSTRUCTIONS :
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE CONDITION :
This antibody is stable for at least one (1) year at -70C. Avoid multiple freeze- thaw cycles.
SPECIFICITY :
This antibody recognizes the 95 kD nibrin protein which contains a forkhead-associated domain that is adjacent to BRCT, a breast cancer C- terminal domain involved in protein- protein interactions. p95/nibrin is a member of the Mre11/Rad50 double- strand break repair complex.
Image Name_1 :
qed-bioscience-anti-p95-nibrin-antibody-56249-1.jpg
Applications 1 :
WB
Image Name_2 :
qed-bioscience-anti-p95-nibrin-antibody-56249-2.jpg
Applications 2 :
IF
Image Name_3 :
qed-bioscience-anti-p95-nibrin-antibody-56249-3.jpg
Applications 3 :
WB
company information
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
headquarters: United States